A Cluster Randomized Trial of Decision Support Strategies for Reducing Antibiotic Use in Acute Bronchitis
| Autor: | Michelle Yefko, Tammy Anderer, Judith H. Maselli, Melissa Stahl, Julie Molecavage, Joshua P. Metlay, Charles E. McCulloch, Thomas R. Graf, Frederick J. Bloom, Ralph Gonzales |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Decision support system Adolescent Clinical Trials and Supportive Activities Clinical Sciences MEDLINE Inappropriate Prescribing Practice Patterns Decision Support Techniques law.invention Randomized controlled trial Clinical Research Opthalmology and Optometry law Intervention (counseling) Health care Internal Medicine medicine Cluster Analysis Humans Cluster randomised controlled trial Practice Patterns Physicians' Bronchitis Physicians' Primary Health Care business.industry Prevention Health Services Pennsylvania medicine.disease Drug Utilization Anti-Bacterial Agents Infectious Diseases Acute Disease Public Health and Health Services Physical therapy Female business Patient education |
| Zdroj: | JAMA internal medicine, vol 173, iss 4 |
| ISSN: | 2168-6106 |
| DOI: | 10.1001/jamainternmed.2013.1589 |
| Popis: | Background National quality indicators show little change in the overuse of antibiotics for uncomplicated acute bronchitis. We compared the effect of 2 decision support strategies on antibiotic treatment of uncomplicated acute bronchitis. Methods We conducted a 3-arm cluster randomized trial among 33 primary care practices belonging to an integrated health care system in central Pennsylvania. The printed decision support intervention sites (11 practices) received decision support for acute cough illness through a print-based strategy, the computer-assisted decision support intervention sites (11 practices) received decision support through an electronic medical record–based strategy, and the control sites (11 practices) served as a control arm. Both intervention sites also received clinician education and feedback on prescribing practices, as well as patient education brochures at check-in. Antibiotic prescription rates for uncomplicated acute bronchitis in the winter period (October 1, 2009, through March 31, 2010) following introduction of the intervention were compared with the previous 3 winter periods in an intent-to-treat analysis. Results Compared with the baseline period, the percentage of adolescents and adults prescribed antibiotics during the intervention period decreased at the printed decision support intervention sites (from 80.0% to 68.3%) and at the computer-assisted decision support intervention sites (from 74.0% to 60.7%) but increased slightly at the control sites (from 72.5% to 74.3%). After controlling for patient and clinician characteristics, as well as clustering of observations by clinician and practice site, the differences for the intervention sites were statistically significant from the control sites (P = .003 for control sites vs printed decision support intervention sites and P = .01 for control sites vs computer-assisted decision support intervention sites) but not between themselves (P = .67 for printed decision support intervention sites vs computer-assisted decision support intervention sites). Changes in total visits, 30-day return visit rates, and proportion diagnosed as having uncomplicated acute bronchitis were similar among the study sites. Conclusions Implementation of a decision support strategy for acute bronchitis can help reduce the overuse of antibiotics in primary care settings. The effect of printed vs computer-assisted decision support strategies for providing decision support was equivalent. Trial Registration clinicaltrials.gov Identifier: NCT00981994 |
| Databáze: | OpenAIRE |
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