Rheumatoid arthritis: relation of serum C-reactive protein and erythrocyte sedimentation rates to radiographic changes

Autor: R. A. Crockson, B McConkey, A. P. Crockson, T J Constable, R S Amos
Rok vydání: 1977
Předmět:
Zdroj: BMJ. 1:195-197
ISSN: 1468-5833
0959-8138
DOI: 10.1136/bmj.1.6055.195
Popis: Serum C reactive protein (CRP) levels and erythrocyte sedimentation rates (ESR) were measured in 56 patients with rheumatoid arthritis. Radiographical damage, based on a count of erosions, was significantly more likely to occur when serum CRP and ESR were persistently raised, irrespective of the presence or absence of rheumatoid factor. Measurements of both CRP and ESR were more helpful than either alone, but CRP was probably the more informative. Serial measurements of CRP and ESR provide a reliable means of discriminating between drugs that provide symptomatic relief only and those with a more profound effect in rheumatoid arthritis.
Databáze: OpenAIRE