Caloric Vestibular Stimulation for the Management of Motor and Non-MotorSymptoms in Parkinson’s Disease: Intention-to-Treat Data
| Autor: | David T. Wilkinson, Aleksandra Podlewska, Lanty L. Smith, Mohamed Sakel, Kristen K. Ade, Tracy Pellat-Higgins, Martin D. Slade, Peter A. LeWitt, Mayur Bodani, Sarah E. Banducci |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Parkinson's disease BF Disease Placebo lcsh:Computer applications to medicine. Medical informatics 03 medical and health sciences Cognition 0302 clinical medicine Physical medicine and rehabilitation medicine Non-invasive brain stimulation lcsh:Science (General) Neurorehabilitation 030304 developmental biology Vestibular system 0303 health sciences Multidisciplinary Intention-to-treat analysis business.industry Neuro-rehabilitation Caloric theory medicine.disease lcsh:R858-859.7 business Sensory neuro-modulation 030217 neurology & neurosurgery Neuroscience lcsh:Q1-390 |
| Zdroj: | Data in Brief, Vol 25, Iss, Pp-(2019) Data in Brief |
| ISSN: | 2352-3409 |
| Popis: | This report provides data related to the safety and effectiveness of repeated time-varying caloric vestibular stimulation (CVS) as a treatment for motor and non-motor features of Parkinson's disease (PD). Forty-six subjects receiving stable anti-Parkinsonian therapy were randomized to active (n = 23) or placebo (n = 23) treatment arms. Subjects self-administered CVS twice-daily over a period of 8 weeks at home via a portable, pre-programmed, solid-state ThermoNeuroModulation (TNM™) device delivering continually-varying thermal waveforms through aluminium ear-probes mounted on a wearable headset. Change scores from baseline to end of treatment and to a 1-month follow-up were determined using standardized clinical measures. The data presented here report sample demographics, detailed safety data and the statistical outcomes from the intention-to-treat and modified intention-to-treat analyses. These data supplement findings of the main per protocol analysis reported in the allied article entitled, ‘Caloric Vestibular Stimulation for the Management of Motor and Non-Motor Symptoms in Parkinson's Disease’ Wilkinson et al. Keywords: Non-invasive brain stimulation, Sensory neuro-modulation, Neuro-rehabilitation, Cognition |
| Databáze: | OpenAIRE |
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