Systemic lupus erythematosus (SLE) at the Kenyatta National Hospital
| Autor: | Paul Etau Ekwom |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Anti-nuclear antibody Black People Arthritis Diabetes Complications Young Adult Rheumatology immune system diseases Internal medicine medicine Humans Lupus Erythematosus Systemic Renal Insufficiency Young adult Child skin and connective tissue diseases Retrospective Studies business.industry Data Collection Retrospective cohort study Hydroxychloroquine General Medicine Exanthema Middle Aged medicine.disease Kenya Antibodies Antinuclear Hypertension Prednisolone Physical therapy Female medicine.symptom business Malar rash medicine.drug |
| Zdroj: | Clinical Rheumatology. 32:1215-1217 |
| ISSN: | 1434-9949 0770-3198 |
| DOI: | 10.1007/s10067-013-2217-3 |
| Popis: | Systemic lupus erythematosus (SLE) is a complex disease with varied clinical presentation and autoantibody production. It has previously been reported as rare in Black Africans. We established a Rheumatology clinic at the Kenyatta National Hospital in April 2010, and a 1 year audit of this clinic was carried out in September 2011. This is a report of this audit of patients who met the American College of Rheumatology (ACR) criteria for SLE. Thirteen patients met the ACR criteria; their mean age was 34 years, and they were all female. The commonest manifestations were malar rash and arthritis in 69.2 %. Antinuclear antibody was present in 79.6 %, and anti-dsDNA was present in 38.5 %. None of them had human immunodeficiency virus infection; 30 % had other comorbidities (hypertension, diabetes, and renal failure). Thirty percent also had an infection during this period. All these 13 were on prednisolone and 92 % of them were on hydroxychloroquine. There was no reported death during the study period. This confirms the presence of SLE in patients in Kenya who meet the ACR criteria. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink