Advantages of Porcine Xenograft over Autograft in Sinus Lift: A Randomised Clinical Trial

Autor:	Sónia Gouveia, Daniel Humberto Pozza, António Felino, Francisco Correia, Ricardo Faria-Almeida
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Sinus Floor Augmentation Technology bone grafting Bone grafting Maxillary sinus bone substitutes medicine.medical_treatment Sinus lift Split mouth randomised clinical trial sinus floor augmentation Article law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial bone regeneration law medicine sinus augmentation General Materials Science Bone regeneration Bone substitutes Microscopy QC120-168.85 Sinus augmentation business.industry QH201-278.5 030206 dentistry Autologous bone Engineering (General). Civil engineering (General) split mouth randomised clinical trial TK1-9971 Clinical trial medicine.anatomical_structure Descriptive and experimental mechanics 030220 oncology & carcinogenesis Electrical engineering. Electronics. Nuclear engineering TA1-2040 business Nuclear medicine Sinus floor augmentation
Zdroj:	Materials Volume 14 Issue 12 Materials, Vol 14, Iss 3439, p 3439 (2021)
ISSN:	1996-1944
DOI:	10.3390/ma14123439
Popis:	This study aimed to compare the performance of intra-oral autologous bone grafts versus porcine xenografts in a two-step lateral window sinus lift. This split-mouth randomised controlled trial sequentially enrolled 12 patients with a 6-month follow-up. For each patient, a simultaneous randomised bilateral maxillary sinus lift was performed and filled with autologous bone from the mandible (control) or a porcine xenograft (test). A bone biopsy sample was collected during the implant placement for histological and histomorphometric analysis. CT scans were performed at the beginning and at the end of the trial to assess radiological evolution. A comparison of initial and six-month CT scans indicated statistically significant increases in bone level for both materials (7.8 ± 2.4 mm for autologous and 8.7 ± 2.2 mm for xenograft, p < 0.05), and there were no significant differences between the performance of the two materials over time (p = 0.26). The histological analysis showed various stages of the remodelling process and no cells or other signs of inflammation or infection were visible in both groups. The porcine xenografts presented similar results for the studied variables when compared to autologous bone, being a reasonable alternative for a sinus lift.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2063b8bfef7ec733e2a1bdd661007d Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.