Genome‐wide profiling of mRNA and lnc RNA expression in dengue fever and dengue hemorrhagic fever
| Autor: | Zhiping Lv, Jia-Jun Ye, Fei Shen, Hai-Jian Yu, Wen-Sheng Yan, Xiao-Lan Zhong, Xiao-Ming Liao, Yun-Fang Zhang |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Candidate gene Microarray Dengue hemorrhagic fever dengue hemorrhagic fever Biology General Biochemistry Genetics and Molecular Biology Dengue fever Dengue 03 medical and health sciences 0302 clinical medicine genome profiling IL12A medicine Humans dengue fever RNA Messenger Severe Dengue KEGG Gene Research Articles Genetics Messenger RNA DElncRNAs Gene Expression Profiling DEGs virus diseases medicine.disease integrated analysis 030104 developmental biology 030220 oncology & carcinogenesis RNA Long Noncoding Biomarkers Research Article |
| Zdroj: | FEBS Open Bio |
| ISSN: | 2211-5463 |
| DOI: | 10.1002/2211-5463.12576 |
| Popis: | Dengue fever (DF) and dengue hemorrhagic fever (DHF) are recurrent diseases that are widespread in the tropics. Here, we identified candidate genes associated with these diseases by performing integrated analyses of DF ({"type":"entrez-geo","attrs":{"text":"GSE51808","term_id":"51808"}}GSE51808) and DHF ({"type":"entrez-geo","attrs":{"text":"GSE18090","term_id":"18090"}}GSE18090) microarray datasets in the Gene Expression Omnibus (GEO). In all, we identified 7635 differentially expressed genes (DEGs) in DF and 8147 DEGs in DHF as compared to healthy controls (P |
| Databáze: | OpenAIRE |
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