Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds
| Autor: | Akanksha Kanitkar, Christopher B. Williams, Timothy Edward Long, Scott S. Verbridge, Ryan J. Mondschein |
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| Rok vydání: | 2017 |
| Předmět: |
Scaffold
Materials science Polymers Biophysics Connective tissue 3D printing Bioengineering Biocompatible Materials 02 engineering and technology 010402 general chemistry 01 natural sciences Regenerative medicine law.invention Polymerization Biomaterials law Soft tissue engineering medicine Animals Humans Stereolithography chemistry.chemical_classification Tissue Engineering Tissue Scaffolds business.industry Bioprinting Soft tissue Polymer 021001 nanoscience & nanotechnology 0104 chemical sciences medicine.anatomical_structure chemistry Mechanics of Materials Printing Three-Dimensional Ceramics and Composites 0210 nano-technology business Biomedical engineering |
| Zdroj: | Biomaterials. 140 |
| ISSN: | 1878-5905 |
| Popis: | This review highlights the synthesis, properties, and advanced applications of synthetic and natural polymers 3D printed using stereolithography for soft tissue engineering applications. Soft tissue scaffolds are of great interest due to the number of musculoskeletal, cardiovascular, and connective tissue injuries and replacements humans face each year. Accurately replacing or repairing these tissues is challenging due to the variation in size, shape, and strength of different types of soft tissue. With advancing processing techniques such as stereolithography, control of scaffold resolution down to the μm scale is achievable along with the ability to customize each fabricated scaffold to match the targeted replacement tissue. Matching the advanced manufacturing technique to polymer properties as well as maintaining the proper chemical, biological, and mechanical properties for tissue replacement is extremely challenging. This review discusses the design of polymers with tailored structure, architecture, and functionality for stereolithography, while maintaining chemical, biological, and mechanical properties to mimic a broad range of soft tissue types. |
| Databáze: | OpenAIRE |
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