The physicochemical properties of a spray dried glutinous rice starch biopolymer
| Autor: | Pornpun Laovachirasuwan, Makoto Otsuka, Jomjai Peerapattana, Padungkwan Chitropas, Voranuch Srijesdaruk |
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| Rok vydání: | 2010 |
| Předmět: |
Hot Temperature
Materials science Chemical Phenomena Surface Properties Scanning electron microscope Starch Rheometer engineering.material chemistry.chemical_compound Colloid Biopolymers Colloid and Surface Chemistry Differential scanning calorimetry X-Ray Diffraction Organic chemistry Physical and Theoretical Chemistry Spectroscopy Near-Infrared Calorimetry Differential Scanning Viscosity Surfaces and Interfaces General Medicine Propranolol Elasticity Amorphous solid Solubility Chemical engineering chemistry X-ray crystallography Microscopy Electron Scanning engineering Gelatin Biopolymer Crystallization Biotechnology |
| Zdroj: | Colloids and Surfaces B: Biointerfaces. 78:30-35 |
| ISSN: | 0927-7765 |
| DOI: | 10.1016/j.colsurfb.2010.02.004 |
| Popis: | Glutinous rice starch (GRS) is a biopolymer used widely in the food industry but not at all in the pharmaceutical industry. There are several ways to modify this biopolymer. Physical modification is simple and cheap because it requires no chemicals or biological agents. The aim of this study was to characterize the physicochemical properties of a spray dried glutinous rice starch (SGRS) produced from pregelatinized GRS. The surface morphology changed from an irregular to concave spherical shape as revealed by Scanning Electron Microscopy (SEM). SGRS was almost amorphous as determined by X-ray Diffraction (XRD) spectroscopy. The water molecules became linked through hydrogen bonds to the exposed hydroxyl group of amorphous SGRS as determined by Near Infrared (NIR) spectroscopy. Then, SGRS formed a colloid gel matrix with water and developed a highly viscous gelatinous form as determined using Differential Scanning Calorimetry (DSC) and a stress control type rheometer. In addition, SGRS can swell and produce a gelatinous surface barrier like a hydrophilic matrix biopolymer which controls drug release. Therefore, a novel application of SGRS is as a sustained release modifier for direct compression tablets in the pharmaceutical industry. |
| Databáze: | OpenAIRE |
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