Transition from contractile to protractile distortions occurring along an actin filament sliding on myosin molecules
| Autor: | Koichiro Matsuno, Katsuhiko Shimada, Hajime Honda, Jun'ichi Sakamaki, Kuniyuki Hatori |
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| Rok vydání: | 2004 |
| Předmět: |
Actin filament sliding
Chemistry Organic Chemistry Biophysics macromolecular substances Myosins Microfilament Biochemistry Actins Protein filament Crystallography Myosin head Adenosine Triphosphate Myosin medicine Animals Molecule Rabbits medicine.symptom Muscle Skeletal Actin Fluorescent Dyes Muscle Contraction Muscle contraction |
| Zdroj: | Biophysical Chemistry. 107:283-288 |
| ISSN: | 0301-4622 |
| Popis: | An ATP-activated actin filament sliding on myosin molecules exhibited mechanical distortions or fluctuations both longitudinally and transversally along the filament. Although actin filaments exhibited a uniform sliding movement longitudinally as the ATP concentration increased, the longitudinal fluctuations were found to vary their magnitude with the concentration. The magnitude of longitudinal fluctuations reached its maximum at approximately 100 microM of the ATP concentration. The local enhancement of the longitudinal fluctuations as responding to changes in the ATP concentration is associated with a critical phenomenon bridging the two different kinds of mechanical distortions, either contractile or protractile ones, occurring within a sliding actin filament. |
| Databáze: | OpenAIRE |
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