Accuracy of combined quantitative diffusion-weighted MRI and routine contrast-enhanced MRI in discrimination of benign and malignant salivary gland tumors
| Autor: | Ramy Edward Assad, Ayda Youssef, Dina Hady, Esmat Mahmoud, Ayman Nada |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Imaging of Neoplastic Diseases Adolescent CONTRAST ENHANCED MRI Management planning 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences 0302 clinical medicine Image Interpretation Computer-Assisted medicine Humans Effective diffusion coefficient Radiology Nuclear Medicine and imaging Child Aged Retrospective Studies Salivary gland business.industry General Medicine Middle Aged Salivary Gland Neoplasms Diffusion Magnetic Resonance Imaging medicine.anatomical_structure Child Preschool 030220 oncology & carcinogenesis Female Neurology (clinical) Radiology business Diffusion MRI |
| Zdroj: | Neuroradiol J |
| ISSN: | 2385-1996 1971-4009 |
| DOI: | 10.1177/1971400920913973 |
| Popis: | Background Preoperative imaging of salivary gland tumors is important for predicting and differentiating benign from malignant tumors, and for aiding management planning. We aimed to investigate the accuracy of combined quantitative diffusion-weighted magnetic resonance imaging (MRI) and routine contrast-enhanced MRI in the evaluation of salivary gland tumors and the differentiation of benign from malignant tumors. Results This study included 51 patients with a total of 16 benign and 35 malignant lesions that were detected by histopathological analysis. There was a statistically significant difference between the apparent diffusion coefficient values (ADC) of malignant and benign lesions (0.69 ± 0.22 × 10−3 mm2/s and 1.39 ± 0.52 × 10−3 mm2/s respectively). The optimal cut-off ADC value was 1.08 with 75% specificity and 97% sensitivity. The routine contrast-enhanced MRI had predicted benign and malignant tumors with 65% sensitivity and 44% specificity. The sensitivity and specificity were greatly increased when quantitative diffusion-weighted MRI was combined with routine contrast-enhanced MRI: 100%, and 88% respectively. A receiver operating curve was generated. The area under curve was 0.88 ( p Conclusion Combined quantitative diffusion-weighted MRI with ADC measurements and routine contrast-enhanced magnetic resonance imaging are helpful tools for the evaluation of salivary gland tumors and help differentiate benign from malignant lesions. |
| Databáze: | OpenAIRE |
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