| Autor: |
Hideo Yanai, Daisuke Chihara, Megumi Harano, Eiki Sakaguchi, Seiji Kaino, Tomoyuki Murakami, Jun Nishikawa |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Cancer Reports. 6 |
| ISSN: |
2573-8348 |
| Popis: |
Early gastric cancer (EGC) with mixed-type histology is a significant risk factor for additional surgery after endoscopic submucosal dissection (ESD). On the other hand, Epstein-Barr virus-associated gastric cancer (EBVaGC) with mixed-type histology is a favorable risk factor with regard to lymph node metastasis.We performed EBV detection in 13 ESD-proven lesions in 13 cases of early gastric cancer with mixed-type histology using EBV-encoded small RNA1 in situ hybridization (EBER1 ISH).EBVaGC was diagnosed in only one (7.7%) of the tested lesions. That EBVaGC patient underwent surgery and there was no residual lesion and no lymph metastasis. EBVaGC is not frequent in EGC with mixed-type histology.EBV testing of gastric biopsy specimens seems not to be useful to predict the mixed-type histology results of ESD. However, EBV testing for ESD specimens of EGC with mixed-type histology is expected to be useful for avoiding excessive additional surgery. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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