Categorical and dimensional psychopathology in Dutch and US offspring of parents with bipolar disorder: A preliminary cross-national comparison

Autor: Dara Sakolsky, Marjolein Wals, Willem A. Nolen, Marloes Vleeschouwer, David Axelson, Rasim Somer Diler, Eske M. Derks, Danella Hafeman, Frank C. Verhulst, Catrien G Reichart, Mary Beth Hickey, Manon H.J. Hillegers, Esther Mesman, Benjamin I. Goldstein, Boris Birmaher, Kelly Monk, Tina R. Goldstein
Přispěvatelé: Adult Psychiatry, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Clinical Cognitive Neuropsychiatry Research Program (CCNP), Child and Adolescent Psychiatry / Psychology, Department of Psychology, Education and Child Studies
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Male
Child Behavior Checklist
Mood disorder
CHILDREN
Comorbidity
0302 clinical medicine
Child of Impaired Parents
Risk Factors
ADOLESCENTS
HISTORY
Ethnicity
Prevalence
EPIDEMIOLOGY
Child
Netherlands
Psychopathology
High risk
ASSOCIATION
Psychiatry and Mental health
Clinical Psychology
Female
Psychology
MENTAL-HEALTH
Clinical psychology
Affective Disorders
Psychotic

Cross-Cultural Comparison
medicine.medical_specialty
Adolescent
Offspring
Bipolar disorder
UNITED-STATES
Child Behavior Disorders
SPECTRUM DISORDERS
Article
03 medical and health sciences
AGE
mental disorders
medicine
Humans
Psychiatry
Cross-national
Schedule for Affective Disorders and Schizophrenia
Reproducibility of Results
medicine.disease
United States
030227 psychiatry
Mood
Mood disorders
ONSET
Schizophrenia
Bipolar offspring
030217 neurology & neurosurgery
Zdroj: Journal of affective disorders, 205, 95-102. Elsevier
Journal of Affective Disorders, 205, 95-102. ELSEVIER SCIENCE BV
Journal of Affective Disorders, 205(2016), 95-102. Elsevier
ISSN: 0165-0327
DOI: 10.1016/j.jad.2016.06.011
Popis: Objective Accumulating evidence suggests cross-national differences in adults with bipolar disorder (BD), but also in the susceptibility of their offspring (bipolar offspring). This study aims to explore and clarify cross-national variation in the prevalence of categorical and dimensional psychopathology between bipolar offspring in the US and The Netherlands. Methods We compared levels of psychopathology in offspring of the Pittsburgh Bipolar Offspring Study (n=224) and the Dutch Bipolar Offspring Study (n=136) (age 10–18). Categorical psychopathology was ascertained through interviews using the Schedule for Affective Disorders and Schizophrenia for School Age Children (K-SADS-PL), dimensional psychopathology by parental reports using the Child Behavior Checklist (CBCL). Results Higher rates of categorical psychopathology were observed in the US versus the Dutch samples (66% versus 44%). We found no differences in the overall prevalence of mood disorders, including BD-I or -II, but more comorbidity in mood disorders in US versus Dutch offspring (80% versus 34%). The strongest predictors of categorical psychopathology were maternal BD (OR: 1.72, p
Databáze: OpenAIRE