Categorical and dimensional psychopathology in Dutch and US offspring of parents with bipolar disorder: A preliminary cross-national comparison
Autor: | Dara Sakolsky, Marjolein Wals, Willem A. Nolen, Marloes Vleeschouwer, David Axelson, Rasim Somer Diler, Eske M. Derks, Danella Hafeman, Frank C. Verhulst, Catrien G Reichart, Mary Beth Hickey, Manon H.J. Hillegers, Esther Mesman, Benjamin I. Goldstein, Boris Birmaher, Kelly Monk, Tina R. Goldstein |
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Přispěvatelé: | Adult Psychiatry, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Clinical Cognitive Neuropsychiatry Research Program (CCNP), Child and Adolescent Psychiatry / Psychology, Department of Psychology, Education and Child Studies |
Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Male
Child Behavior Checklist Mood disorder CHILDREN Comorbidity 0302 clinical medicine Child of Impaired Parents Risk Factors ADOLESCENTS HISTORY Ethnicity Prevalence EPIDEMIOLOGY Child Netherlands Psychopathology High risk ASSOCIATION Psychiatry and Mental health Clinical Psychology Female Psychology MENTAL-HEALTH Clinical psychology Affective Disorders Psychotic Cross-Cultural Comparison medicine.medical_specialty Adolescent Offspring Bipolar disorder UNITED-STATES Child Behavior Disorders SPECTRUM DISORDERS Article 03 medical and health sciences AGE mental disorders medicine Humans Psychiatry Cross-national Schedule for Affective Disorders and Schizophrenia Reproducibility of Results medicine.disease United States 030227 psychiatry Mood Mood disorders ONSET Schizophrenia Bipolar offspring 030217 neurology & neurosurgery |
Zdroj: | Journal of affective disorders, 205, 95-102. Elsevier Journal of Affective Disorders, 205, 95-102. ELSEVIER SCIENCE BV Journal of Affective Disorders, 205(2016), 95-102. Elsevier |
ISSN: | 0165-0327 |
DOI: | 10.1016/j.jad.2016.06.011 |
Popis: | Objective Accumulating evidence suggests cross-national differences in adults with bipolar disorder (BD), but also in the susceptibility of their offspring (bipolar offspring). This study aims to explore and clarify cross-national variation in the prevalence of categorical and dimensional psychopathology between bipolar offspring in the US and The Netherlands. Methods We compared levels of psychopathology in offspring of the Pittsburgh Bipolar Offspring Study (n=224) and the Dutch Bipolar Offspring Study (n=136) (age 10–18). Categorical psychopathology was ascertained through interviews using the Schedule for Affective Disorders and Schizophrenia for School Age Children (K-SADS-PL), dimensional psychopathology by parental reports using the Child Behavior Checklist (CBCL). Results Higher rates of categorical psychopathology were observed in the US versus the Dutch samples (66% versus 44%). We found no differences in the overall prevalence of mood disorders, including BD-I or -II, but more comorbidity in mood disorders in US versus Dutch offspring (80% versus 34%). The strongest predictors of categorical psychopathology were maternal BD (OR: 1.72, p |
Databáze: | OpenAIRE |
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