Assignment of the mouse alpha A-crystallin structural gene to chromosome 17
| Autor: | Joram Piatigorsky, Nancy Weber Kaye, Peter A. Lalley, J. Mark Petrash, Robert L. Church |
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| Rok vydání: | 1985 |
| Předmět: |
Biology
Hybrid Cells Chinese hamster Cell Line Cellular and Molecular Neuroscience Mice Cricetulus Gene mapping Crystallin Complementary DNA Cricetinae Animals Gene Southern blot Mice Inbred BALB C Structural gene Chromosome Mapping biology.organism_classification Molecular biology Crystallins eye diseases Sensory Systems Chromosome 17 (human) Ophthalmology Genes sense organs DNA Circular |
| Zdroj: | Current eye research. 4(12) |
| ISSN: | 0271-3683 |
| Popis: | alpha A2-crystallin is one of the major water-soluble proteins of the mammalian lens. Using a cloned cDNA probe coding for mouse alpha A2-crystallin and Southern blot hybridization, DNA isolated from a panel of somatic cell hybrids prepared from mouse fibroblasts or mouse spleen cells fused with Chinese hamster fibroblasts was probed to determine the chromosomal localization of the alpha A2-crystallin structural gene. We have located this gene on mouse chromosome 17. |
| Databáze: | OpenAIRE |
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