Effect of vitamin D deficiency on spontaneous peritonitis in cirrhosis: a meta-analysis

Autor:	Lili Wu, Guoping Wang, Zhongchen Zhang, Ping Hu
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Review Paper medicine.medical_specialty Cirrhosis business.industry cirrhosis Gastroenterology Peritonitis vitamin d medicine.disease vitamin D deficiency Meta-analysis Internal medicine Inclusion and exclusion criteria Vitamin D and neurology Medicine spontaneous peritonitis business
Zdroj:	Gastroenterology Review, Vol 16, Iss 1, Pp 10-14 (2020) Przegla̜d Gastroenterologiczny
ISSN:	1897-4317 1895-5770
Popis:	Introduction Few studies have reported the relationship between spontaneous peritonitis in cirrhosis and vitamin D, and the result is not very convincing. Aim To conduct a meta-analysis to clarify the relationship between vitamin D and spontaneous peritonitis. Material and methods Articles published up to 1 October 2019 in the PubMed, Medline, and Embase databases were searched. According to the inclusion and exclusion criteria, relevant statistical data were extracted and analysed by STATA. Results Six articles met the inclusion criteria. It was demonstrated that the average 25(OH)D level in spontaneous peritonitis patients was 2.36 less than that in control individuals (SMD = –2.36, 95% CI: –3.92, –0.8, I2 = 97.2%, p < 0.01). Moreover, it found that spontaneous peritonitis patients were 4.33 times more likely to be vitamin D deficient than controls (OR = 4.33, 95% CI: 1.57, 11.93, I2 = 50.1%, p = 0.111). Sensitivity analysis showed that the meta-analysis results were stable and reliable. Conclusions Vitamin D may be an importantly protective factor in spontaneous peritonitis.
Databáze:	OpenAIRE
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