Reduced mechanical function of the left atrial predicts adverse outcome in pregnant women with clustering of metabolic risk factors

Autor: Xue-Yan Ding, Lan-Lan Sun, Dichen Guo, Yidan Li, Yun-Yun Qin, Xiao-Guang Ye, Xiuzhang Lu, Qi-Zhe Cai, Zhitian Li, Weiwei Zhu
Rok vydání: 2021
Předmět:
Adult
medicine.medical_specialty
Metabolic risk factors
030204 cardiovascular system & hematology
Risk Assessment
Fetal Distress
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Pregnancy
Left atrial
medicine
Fetal distress
Humans
Diseases of the circulatory (Cardiovascular) system
Heart Atria
030212 general & internal medicine
Abruptio Placentae
Left atrial function
Retrospective Studies
Angiology
Placental abruption
Obstetrics
business.industry
Proportional hazards model
Research
Pregnancy Outcome
Cardiometabolic Risk Factors
Hypertension
Pregnancy-Induced
medicine.disease
Cardiac surgery
Gestational diabetes
Diabetes
Gestational
Blood pressure
Echocardiography
RC666-701
Premature Birth
Atrial Function
Left
Female
Cardiology and Cardiovascular Medicine
business
Zdroj: BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cardiovascular Disorders
ISSN: 1471-2261
DOI: 10.1186/s12872-021-02082-7
Popis: Introduction The left atrial (LA) strain and strain rate are sensitive indicators of LA function. However, they are not widely used for the evaluation of pregnant women with metabolic diseases. The aim of this study was to assess the LA strain and strain rate of pregnant women with clustering of metabolic risk factors and to explore its prognostic effect on adverse pregnancy outcomes. Materials and methods Sixty-three pregnant women with a clustering of metabolic risk factors (CMR group), fifty-seven women with pregnancy-induced hypertension (PIH group), fifty-seven women with gestational diabetes mellitus (GDM group), and fifty matched healthy pregnant women (control group) were retrospectively evaluated. LA function was evaluated with two-dimensional speckle-tracking imaging. Iatrogenic preterm delivery caused by severe preeclampsia, placental abruption, and fetal distress was regarded as the primary adverse outcome. Results The CMR group showed the lowest LA strain during reservoir phase (LASr), strain during contraction phase (LASct) and peak strain rate during conduit phase (pLASRcd) among the three groups (P P Conclusions LA mechanical function in pregnant women with metabolic aggregation is deteriorated. An LASr value of 38.35% or less may indicate the occurrence of adverse pregnancy outcomes.
Databáze: OpenAIRE
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