| Autor: |
Kalle T Rytkönen, Nigatu Adossa, Mehrad Mahmoudian, Tapio Lönnberg, Matti Poutanen, Laura L Elo |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Reproduction (Cambridge, England). 164(5) |
| ISSN: |
1741-7899 |
| Popis: |
In brief Preeclampsia is a common serious disorder that can occur during pregnancy. This study uses integrative analysis of preeclampsia transcriptomes and single-cell transcriptomes to predict cell type-specific contributions to preeclampsia. Abstract Preeclampsia is a devastating pregnancy disorder and a major cause of maternal and perinatal mortality. By combining previous transcriptomic results on preeclampsia with single-cell sequencing data, we here predict distinct and partly unanticipated contributions of decidual stromal cells and uterine natural killer cells in early- and late-onset preeclampsia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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