Differences in the Effectiveness of Long-Acting Injection and Orally Administered Antipsychotics in Reducing Rehospitalization among Patients with Schizophrenia Receiving Home Care Services

Autor:	Hsiao-Fen Hsu, Jeremy C. Ying, Chia-Chan Kao, Ti Lu, Sheng-Yu Lee
Rok vydání:	2019
Předmět:	rehospitalization Oral treatment Pediatrics medicine.medical_specialty medicine.medical_treatment Southern taiwan lcsh:Medicine oral antipsychotics Article psychiatric home care service First generation antipsychotic Treatment and control groups 03 medical and health sciences 0302 clinical medicine Female patient medicine long-acting antipsychotics Antipsychotic business.industry lcsh:R General Medicine medicine.disease 030227 psychiatry schizophrenia Long acting Schizophrenia business 030217 neurology & neurosurgery
Zdroj:	Journal of Clinical Medicine Volume 8 Issue 6 Journal of Clinical Medicine, Vol 8, Iss 6, p 823 (2019)
ISSN:	2077-0383
DOI:	10.3390/jcm8060823
Popis:	The current study explored the differences in the effectiveness of first and second generation long-acting injections and orally administered antipsychotics in reducing the rehospitalization rate among patients with schizophrenia receiving home care services in a medical center in Southern Taiwan. Longitudinal data between 1 January 2006, and 31 December 2015, were collected retrospectively. Patients were classified into three treatment groups: First generation antipsychotic (FGA) long-acting injection (LAI), second generation antipsychotic long-acting injection (SGA) (LAI), and oral antipsychotics. The primary outcomes were the rehospitalization rate and the follow-up time (duration of receiving home care services) until psychiatric rehospitalization. A total of 78 patients with schizophrenia were recruited. The average observation time was about 40 months. The oral treatment group tended to be older with a higher number of female patients and a lower level of education. The FGA treatment group tended to have a higher frequency and duration of hospitalization before receiving home care services. We found no significant differences in the follow-up time or psychiatric rehospitalization rate after receiving home care services among the three treatment groups. We propose that oral and LAI antipsychotics were equally effective when patients received home care services. Our results can serve as a reference for the choice of treatment for patients with schizophrenia in a home care program.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df513962a69f9971f3063d963ae056b https://doi.org/10.3390/jcm8060823 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.