Synovitis in a Patient with IgG4-related Disease
| Autor: | Ryu Watanabe, Tomonori Ishii, Yuko Shirota, Hiroshi Sato, Yukiko Kamogawa, Fumiko Tomiyama, Hiroshi Fujii, Yoko Fujita, Takashi Nakamichi, Hideo Harigae |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
musculoskeletal diseases
Male medicine.medical_specialty Pathology Shoulder Biopsy Physical examination Kidney Autoimmune Diseases chemistry.chemical_compound Synovitis parasitic diseases Internal Medicine Medicine Humans skin and connective tissue diseases Aged Creatinine medicine.diagnostic_test business.industry General Medicine Wrist medicine.disease Magnetic Resonance Imaging chemistry Rheumatoid arthritis Immunoglobulin G Positron-Emission Tomography Nephritis Interstitial IgG4-related disease Renal biopsy Radiology business Nephritis |
| Zdroj: | Internal medicine (Tokyo, Japan). 54(11) |
| ISSN: | 1349-7235 |
| Popis: | A 71-year-old man was admitted to our department due to arthralgia and renal dysfunction. A physical examination disclosed swelling of the right shoulder and left wrist joints. Laboratory tests showed elevated serum IgG4 and creatinine levels, and magnetic resonance imaging of the wrist revealed bone erosion and synovitis. In addition, fluorodeoxyglucose positron emission tomography showed uptake in the submandibular glands, pancreas, kidneys, and affected joints and a renal biopsy revealed tubulointerstitial nephritis with the infiltration of IgG4+ plasma cells. The patient was subsequently diagnosed with IgG4-related disease (IgG4-RD) and successfully treated with corticosteroid therapy. This case suggests that erosive arthritis may occur in patients with IgG4-RD. |
| Databáze: | OpenAIRE |
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