A morphological study of the action of equine anti-lipopolysaccharide plasma on gram-negative bacteria
| Autor: | S. L. Gaffin, M. T. Wells |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Lipopolysaccharides
Microbiology (medical) Gram-negative bacteria Lipopolysaccharide Klebsiella pneumoniae Enterobacter medicine.disease_cause Cell morphology Microbiology Cell membrane chemistry.chemical_compound Enterobacteriaceae Escherichia coli medicine Animals Horses biology Immune Sera General Medicine biology.organism_classification medicine.anatomical_structure chemistry Microscopy Electron Scanning Bacteria |
| Zdroj: | Journal of Medical Microbiology. 24:165-168 |
| ISSN: | 1473-5644 0022-2615 |
| DOI: | 10.1099/00222615-24-2-165 |
| Popis: | Three strains of gram-negative bacteria--one each of Escherichia coli, Klebsiella pneumoniae and Enterobacter sp.--were treated with anti-lipopolysaccharide hyperimmune equine plasma (anti-LPS) or non-immune control plasma and examined by scanning electronmicroscopy. Within a few minutes of treatment with anti-LPS, bacteria were agglutinated. Evidence of cell membrane destruction was observed shortly thereafter and total cell disintegration and disruption occurred within 1-2 h. In contrast, non-immune plasma had no effect on cell morphology. This confirms the findings in previous microbiological studies that specific antibodies in anti-LPS bind to lipopolysaccharide (LPS endotoxin), and thereby initiate the destruction of gram-negative bacteria. |
| Databáze: | OpenAIRE |
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