Airway obstruction in asthmatic and healthy individuals: inspiratory and expiratory thin-section CT findings
| Autor: | Nestor L. Müller, Chan Sup Park, N. Awadh, Joung Sook Kim, M. Fitzgerald, S. A. Worthy |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Air trapping Pulmonary function testing medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Expiration Asthma Bronchus Lung business.industry Respiration Respiratory disease Middle Aged respiratory system Airway obstruction medicine.disease Respiratory Function Tests respiratory tract diseases Airway Obstruction medicine.anatomical_structure Female Radiology medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Radiology. 203:361-367 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiology.203.2.9114089 |
| Popis: | To determine differences in computed tomographic (CT) findings in asthmatic and healthy individuals and to correlate the findings with severity of airway obstruction.Thirty-nine asthmatic patients and 14 healthy subjects were prospectively evaluated with thin-section CT. Inspiratory CT scans were subjectively evaluated for presence of bronchial wall thickening, bronchial dilatation, and mosaic lung attenuation; expiratory scans were subjectively evaluated for presence of air trapping. Objective measurement of bronchoarterial-diameter ratio was performed on inspiratory scans. CT findings were compared with pulmonary function test results.Bronchial wall thickening, severe air trapping, and reduced bronchoarterial-diameter ratio were observed more commonly in asthmatic patients than in healthy subjects. Bronchial wall thickening was more prevalent among patients with severe airflow obstruction (10 of 12 readings [83%]) than in patients with normal airflow (15 of 40 readings [38%]) or mild obstruction (nine of 26 readings [35%]). Other subjectively determined CT findings did not correlate with pulmonary function test results. The mean bronchoarterial-diameter ratios +/- 1 standard deviation were 0.65 +/- 0.16 in healthy subjects and 0.60 +/- 0.16, 0.60 +/- 0.18, and 0.48 +/- 0.11 in patients with normal airflow and mild and severe obstruction, respectively.Thin-section CT is of limited value in distinguishing asthmatic patients with normal airflow or mild airflow obstruction from healthy subjects. |
| Databáze: | OpenAIRE |
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