Ginkgo Biloba melhora a formação dos ossos durante a consolidação da fratura: estudo em ratos
Autor: | Osman Aynaci, Emrah Sayit, Esin Yulug, Servet Kerimoğlu, Nizamettin Guzel, Murat Topbaş |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
medicine.medical_specialty Transverse fracture Urology Physical Therapy Sports Therapy and Rehabilitation Fracture healing Bone healing 03 medical and health sciences 0302 clinical medicine medicine Orthopedics and Sports Medicine Kirschner wire Bone formation Consolidação da fratura Ratos Orthopedic surgery biology business.industry Ginkgo biloba Rehabilitation Significant difference Right femur biology.organism_classification Rats 030104 developmental biology 030220 oncology & carcinogenesis Medicine Original Article Once daily business RD701-811 |
Zdroj: | Acta Ortopédica Brasileira, Vol 25, Iss 3, Pp 95-98 (2017) Acta Ortopédica Brasileira, Volume: 25, Issue: 3, Pages: 95-98, Published: JUN 2017 Acta Ortopédica Brasileira v.25 n.3 2017 Acta Ortopédica Brasileira Sociedade Brasileira de Ortopedia e Traumatologia (SBOT) instacron:SBOT Acta Ortopedica Brasileira |
ISSN: | 1413-7852 |
Popis: | OBJECTIVES: Ginkgo biloba extract (EGb 761) is a plant extract obtained from the leaves of the G. biloba tree. The aim of this study was to assess the histological and radiological effects of G. biloba extract on fracture healing in an experimental fracture model using rat femurs. METHODS: Forty-eight female Sprague-Dawley rats (weight: 195-252 g; age: 20 weeks) were used in the study. The rats were randomly divided into six groups (n=8). A transverse fracture was made in the middle of the right femur of each rat and fixed with a Kirschner wire. The G. biloba groups received 60 mg/kg oral G. biloba extract once daily. No medication was given to the control groups. On days 7, 21 and 35, both sets of femurs were evaluated radiologically and histopathologically. RESULTS: Histological evaluation revealed that the G. biloba groups had significant differences at 21 and 35 days (p |
Databáze: | OpenAIRE |
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