Ginkgo Biloba melhora a formação dos ossos durante a consolidação da fratura: estudo em ratos

Autor: Osman Aynaci, Emrah Sayit, Esin Yulug, Servet Kerimoğlu, Nizamettin Guzel, Murat Topbaş
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Acta Ortopédica Brasileira, Vol 25, Iss 3, Pp 95-98 (2017)
Acta Ortopédica Brasileira, Volume: 25, Issue: 3, Pages: 95-98, Published: JUN 2017
Acta Ortopédica Brasileira v.25 n.3 2017
Acta Ortopédica Brasileira
Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron:SBOT
Acta Ortopedica Brasileira
ISSN: 1413-7852
Popis: OBJECTIVES: Ginkgo biloba extract (EGb 761) is a plant extract obtained from the leaves of the G. biloba tree. The aim of this study was to assess the histological and radiological effects of G. biloba extract on fracture healing in an experimental fracture model using rat femurs. METHODS: Forty-eight female Sprague-Dawley rats (weight: 195-252 g; age: 20 weeks) were used in the study. The rats were randomly divided into six groups (n=8). A transverse fracture was made in the middle of the right femur of each rat and fixed with a Kirschner wire. The G. biloba groups received 60 mg/kg oral G. biloba extract once daily. No medication was given to the control groups. On days 7, 21 and 35, both sets of femurs were evaluated radiologically and histopathologically. RESULTS: Histological evaluation revealed that the G. biloba groups had significant differences at 21 and 35 days (p
Databáze: OpenAIRE