Clinical connection between rheumatoid arthritis and liver damage
Autor: | Snežana Tešić-Rajković, Biljana Radovanovic-Dinic, Valentina Zivkovic, Sasa Grgov |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Cirrhosis Immunology Arthritis Gastroenterology Asymptomatic Arthritis Rheumatoid 03 medical and health sciences Liver disease 0302 clinical medicine Rheumatology Liver Function Tests Predictive Value of Tests Risk Factors Internal medicine medicine Immunology and Allergy Humans Liver damage 030203 arthritis & rheumatology Hepatitis business.industry Liver Diseases medicine.disease Prognosis Early Diagnosis Rheumatoid arthritis Antirheumatic Agents 030211 gastroenterology & hepatology medicine.symptom Chemical and Drug Induced Liver Injury business |
Zdroj: | Rheumatology international. 38(5) |
ISSN: | 1437-160X |
Popis: | When liver damage is present in rheumatoid arthritis (RA) patients, it is sometimes difficult to determine whether it is a hepatic manifestation of RA, associated primary liver disease or hepatotoxic liver disease which developed during the treatment of RA. Liver damage during RA is most common in the form of asymptomatic abnormal liver tests. Occasionally, liver damage may progress to cirrhosis. Patients with RA are more susceptible to an associated autoimmune liver disease. Medications used in rheumatology are often hepatotoxic and it is difficult to differentiate between hepatic manifestations of the primary disease and potential hepatotoxicity of the administered medications. The significance of the paper is in the fact that it includes the most relevant and the latest information on this commonly present problem in clinical practice. The aim of the author is to provide comprehensive but at the same time concise data which will be useful to the doctors who come into contact with RA patients with symptomatic or asymptomatic liver disease. Timely diagnosis and treatment of liver disease in RA patients can significantly influence the course and outcome of rheumatoid arthritis. |
Databáze: | OpenAIRE |
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