Isometric contractile properties of fast- and slow-twitch muscles in normal and spastic mice
| Autor: | K.W. Ranatunga, S.R. Wylie |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Male
Chemistry musculoskeletal neural and ocular physiology Muscles Twitch tension Anatomy Isometric exercise Organ Size musculoskeletal system Mice Inbred C57BL Mice Developmental Neuroscience Neurology Muscle Spasticity Organ Specificity medicine Spastic Animals Spasticity medicine.symptom tissues Muscle Contraction |
| Zdroj: | Experimental neurology. 70(2) |
| ISSN: | 0014-4886 |
| Popis: | Isometric contractile properties of the fast-twitch extensor digitorum longus (EDL) and slow-twitch soleus (SOL) muscles of 24 male C57 mice were studied in vitro at 35°C. Ten animals exhibited the hereditary movement disorder known as spasticity. EDL muscles of spastic and normal mice developed similar specific tensions and they had similar twitch tension:tetanic tension ratios. The time-to-peak tension and the time to half relaxation in the twitch of spastic EDL muscles were, on average, slightly longer. SOL muscles of spastic and normal mice also developed similar specific tensions and their twitch contractions had similar times to half-relaxation. The time-to-peak tension in the twitch and the twitch tension: tetanic tension ratio of spastic SOL muscles were, on average, higher than in normal SOL. The significance of our findings remains somewhat uncertain. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|