Physical activity and associations with treatment-induced adverse effects among prostate cancer patients
| Autor: | Sophie D. Fosså, Lene Thorsen, Torbjørn Wisløff, Synne-Kristin Hoffart Bøhn |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Physical activity Odds Androgen deprivation therapy 03 medical and health sciences Prostate cancer 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Adverse effect Exercise Aged Aged 80 and over Prostatectomy Modalities business.industry Prostatic Neoplasms Androgen Antagonists Middle Aged medicine.disease Combined Modality Therapy Radiation therapy Cross-Sectional Studies Oncology 030220 oncology & carcinogenesis business |
| Zdroj: | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 27(3) |
| ISSN: | 1433-7339 |
| Popis: | The present study aimed to determine the level of physical activity (PA) among prostate cancer (PCa) patients across treatment modalities and explore the association between PA and treatment-induced adverse effects (AEs). The present study was based on a cross-sectional postal survey among members of the Norwegian Prostate Cancer Association. Patients were eligible for the present study if they had either (1) completed radical prostatectomy, (2) completed radiotherapy and (neo)-adjuvant androgen deprivation therapy (ADT), or (3) were undergoing lifelong ADT. Adverse effects were measured by the Expanded Prostate Cancer Index Composite for Clinical Practice. In total, 696 patients were included. There was no statistically significant difference in level of PA across treatment modalities. Bowel symptoms mainly related to radiotherapy decreased the odds of exercising ≥ 2 times per week, along with age ≥ 70 years, participation in the workforce, and BMI ≥ 25 kg/m2. Among patients who were undergoing ADT, 5 years or more since diagnosis reduced the odds of exercising ≥ 2 times per week by almost 60%. The level of PA did not differ across PCa patients treated with different modalities. Increasing bowel symptoms reduced the likelihood of exercising ≥ 2 times per week. PCa patients should be educated about possible treatment-induced AEs affecting PA level, enabling them to counteract the development of physical inactivity. |
| Databáze: | OpenAIRE |
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