Insomnia is associated with increased mortality in patients with first-ever stroke: a 6-year follow-up in a Chinese cohort study
| Autor: | Chun-Xue Wang, Li-Jun Li, Yang Yang, Yong-Jun Wang, An-Xin Wang, Bo-Yuan Guan, Ning Zhang, Qi Chen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty China Difficulty Falling Asleep Time Factors insomnia Risk Assessment 03 medical and health sciences 0302 clinical medicine Recurrence Risk Factors Sleep Initiation and Maintenance Disorders medicine Insomnia Risk of mortality Prevalence Humans Medical history 030212 general & internal medicine Prospective Studies Risk factor Stroke Aged business.industry Middle Aged medicine.disease first-ever stroke Prognosis Stroke in China mortality risk factor Original Article Female Neurology (clinical) medicine.symptom Cardiology and Cardiovascular Medicine business Sleep 030217 neurology & neurosurgery Cohort study Follow-Up Studies |
| Zdroj: | Stroke and Vascular Neurology |
| ISSN: | 2059-8696 |
| Popis: | ObjectiveInsomnia is a highly prevalent disorder among patients suffering from stroke. The association between insomnia and stroke mortality is less studied, particularly using the latest diagnostic criteria. The current study examined the relationship between insomnia and mortality among patients with first-evonal hazard models were used to calculate HRs for stroke er stroke in China.MethodsPatients with acute cerebrovascular diseases (stroke) were recruited from 56 hospitals in mainland China. Insomnia was defined as difficulty falling asleep, or difficulty staying asleep or waking up early, for at least two consecutive visits. Demographic data, medical history and clinical data were collected. Four follow-up visits occurred within the first year after stroke, and the last follow-up call was conducted 6 years later. Cox proportional hazard models were used to calculate HRs for stroke mortality.ResultsInsomnia was reported by 38.4% (489/1273) of patients at baseline. During the 6 years of follow-up, after adjusting for all confounders, insomnia was found to be associated with increased mortality (HR=1.66, 95% CI 1.10 to 2.48). Old age (HR=1.08, 95% CI 1.06 to 1.10), stroke recurrence in the first year of follow-up (HR=2.53, 95% CI 1.48 to 4.31) and stroke survivors with hypertension (HR=1.62, 95% CI 1.04 to 2.53) had substantially higher risk of mortality.ConclusionsBesides old age, stroke recurrence in the first year of follow-up and hypertension, insomnia is associated with increased risk of mortality in patients with first-ever stroke in China. More studies about prompt and efficient interventions for insomnia are expected in the future.Trial registration number rctn62169508. |
| Databáze: | OpenAIRE |
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