Delftia Acidovorans pneumonia with lung cavities formation

Autor: Yildiz, Hanifi, Sünnetçioğlu, Aysel, Ekin, Selami, Baran, Ali İrfan, Özgökçe, Mesut, Aşker, Selvi, Üney, İbrahim, Turgut, Engin, Akyüz, Sümeyye
Rok vydání: 2020
Předmět:
medicine.medical_specialty
pneumonia por bacterias
Delftia acidovorans
Case Report
respiratory tract infections
tos
multiple pulmonary nodules
03 medical and health sciences
bacterial pneumonia
infecciones del tracto respiratorio
cough
medicine
huesped immunocomprometido
piperacilina
gram-negative bacterial infections
immunocompromised host
Piperacillin
lung diseases interstitial
Multiple Pulmonary Nodules
030505 public health
Lung
biology
business.industry
infecciones bacteria gram-negativas
Cavitary pneumonia
Bacterial pneumonia
General Medicine
medicine.disease
biology.organism_classification
respiratory sounds
Pneumonia
medicine.anatomical_structure
Delftia
enfermedad pulmonar intersticial
Piperacillin Tazobactam drug combination
nódulos múltiples pulmonares
Sputum
sonidos respiratorios
Radiology
medicine.symptom
0305 other medical science
business
combinación de medicamentos piperailina-tazobactam
Zdroj: Colombia Médica : CM
ISSN: 1657-9534
DOI: 10.25100/cm.v50i3.4025
Popis: Case Description: A 52-year-old female patient was admitted to our clinic with complaints of cough, sputum, fever and fatigue. The patient has been receiving immunosuppressive therapy for thrombocytopenic purpura for 5 years. Clinical Finding: Inspiratory crackles were heard on both hemithorax. Oxygen saturation measured with the pulse oximeter was 97%. Chest X-ray showed diffuse reticular opacities that were more prominent in the upper zones of both lungs. WBC counts were 17600/mm3 and Platelet counts were 29000/mm3. Thorax CT showed that there were many thin-walled cavities and millimetric nodules accompanied by ground-glass infiltrates in the upper and middle lobes. Gram staining of bronchial fluid, taken by bronchoscopy, revealed Gram-negative bacilli and intense polymorphonuclear leukocytes. The bacteria were defined as Delftia acidovorans by BD Phoenix automated system. Treatment and outcomes: The patient was hospitalized with suspicion of opportunistic pulmonary infections and cavitary lung disease. After the empirical treatment of intravenous piperacillin-tazobactam and oral clarithromycin, her clinical and radiological findings significantly regressed, and she was discharged with outpatient follow-up. Clinical Relevance: This is the first example of cavitary pneumonia due to Delftia acidovorans in an immunocompromised patient. We would like to emphasize that Delftia pneumonia should be considered in the differential diagnosis of pulmonary cavitary involvement in such patients.
Databáze: OpenAIRE