Atrial septal defect in adulthood: a new paradigm for congenital heart disease
| Autor: | David S. Celermajer, Helmut Baumgartner, Massimo Chessa, Paul Khairy, Massimo Griselli, Wei Li, Margarita Brida, Tal Geva, Michael A. Gatzoulis |
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| Přispěvatelé: | Brida, Margarita, Chessa, Massimo, Celermajer, David, Li, Wei, Geva, Tal, Khairy, Paul, Griselli, Massimo, Baumgartner, Helmut, Gatzoulis, Michael A |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Cardiac Catheterization medicine.medical_specialty Heart disease medicine.medical_treatment Pulmonary arterial hypertension Heart Septal Defects Atrial Atrial septal defects Advanced imaging Targeted therapy Right heart failure Device closure Internal medicine medicine Humans cardiovascular diseases Sinus venosus defect Atrial tachycardia Pulmonary Arterial Hypertension Atrial septal defect surgery business.industry Treatment options Arrhythmias Cardiac Ablation medicine.disease Catheter Treatment Outcome Atrial septal defect Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | European Heart Journal. 43:2660-2671 |
| ISSN: | 1522-9645 0195-668X |
| DOI: | 10.1093/eurheartj/ehab646 |
| Popis: | Atrial septal defects (ASDs) represent the most common congenital heart defect diagnosed in adulthood. Although considered a simple defect, challenges in optimal diagnostic and treatment options still exist due to great heterogeneity in terms of anatomy and time-related complications primarily arrhythmias, thromboembolism, right heart failure and, in a subset of patients, pulmonary arterial hypertension (PAH). Atrial septal defects call for tertiary expertise where all options may be considered, namely catheter vs. surgical closure, consideration of pre-closure ablation for patients with atrial tachycardia and suitability for closure or/and targeted therapy for patients with PAH. This review serves to update the clinician on the latest evidence, the nuances of optimal diagnostics, treatment options, and long-term follow-up care for patients with an ASD. |
| Databáze: | OpenAIRE |
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