Structure and transfer of the vanA cluster in vanA-positive, vancomycin-susceptible Enterococcus faecium, and its revertant mutant
| Autor: | Hwa Su Kim, Yeong Seon Lee, Jung Sik Yoo, Sung Young Lee, Jae Il Yoo, Jae-yon Yu, Okgene Kim, Young-Hee Jung |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Microbiology (medical)
Mutant Revertant Enterococcus faecium Biology Disease cluster Microbiology Bacterial Proteins Vancomycin Humans Carbon-Oxygen Ligases Vancomycin-Susceptible Enterococcus Gram-Positive Bacterial Infections Vancomycin Resistance General Medicine biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Glycopeptide Anti-Bacterial Agents carbohydrates (lipids) Infectious Diseases Genes Bacterial Multigene Family bacteria |
| Zdroj: | Diagnostic microbiology and infectious disease. 80(2) |
| ISSN: | 1879-0070 |
| Popis: | Of 18 vanA-positive vancomycin-susceptible Enterococcus faecium isolates, vanRS in the vanA cluster was detected in all isolates, while vanHAX was detected in only 2 isolates. Following exposure to glycopeptides, 22.2% of vancomycin-susceptible E. faecium (VSE) converted into vancomycin-resistant E. faecium. The vanA cluster of the revertant mutant was transferred to the VSE isolates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect