Does the primary soft-tissue sarcoma configuration predict configuration of recurrent tumors on magnetic resonance imaging?
| Autor: | Sam Sedaghat, Maya Sedaghat, Olav Jansen, Jens Meschede, Marcus Both, Mona Salehi Ravesh |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Soft tissue sarcoma Sarcoma Soft Tissue Neoplasms Magnetic resonance imaging General Medicine medicine.disease Magnetic Resonance Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Recurrence 030220 oncology & carcinogenesis medicine Humans Radiology Nuclear Medicine and imaging Radiology Neoplasm Recurrence Local business Retrospective Studies |
| Zdroj: | Acta Radiologica. 63:642-651 |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1177/02841851211008381 |
| Popis: | Background Soft-tissue sarcomas (STS) are rare malignancies of the soft tissue. Purpose To assess whether the magnetic resonance imaging (MRI) configuration of primary STS can predict the configuration of a recurring tumor and whether the MRI configuration of multiple recurrences differs in one and the same patient. Material and Methods Thirty-nine patients with histologically proven recurrent STS were included in this retrospective study and underwent pre- and post-treatment MRI. Three main configurations of primary and recurrent tumors were identified: polycyclic/multilobulated; ovoid/nodular; and streaky. Results Sixty recurrent lesions were detected: 34 ovoid/nodular; 15 polycyclic/multilobulated; and 11 streaky. Five recurrences were multifocal and eight were bifocal. Of 39 patients, 28 (71.8%) presented one recurrence within the MRI follow-up period ( P = 0.006); in 10 patients (25.6%), up to three different configurations of recurring STS were identified in one patient. Recurrences of polycyclic/multilobulated primaries were mostly ovoid/nodular (48%; P = 0.003) or polycyclic/multilobulated (37%; P = 0.014), and recurring ovoid/nodular STS significantly most often showed the same configuration as the primary tumor (85%; P Conclusion Primary STS configuration may help predict recurrent tumor configuration when the primary STS had a polycyclic/multilobulated or ovoid/nodular configuration. However, recurrent STS configuration can also differ from primary STS configuration, especially when the primary STS had a streaky configuration, rendering recurrent STS difficult to predict. Different configurations of recurrent STS in one and the same patient are common. |
| Databáze: | OpenAIRE |
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