Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates — United States, 2006–2015

Autor: Erin B. Stallings, Kirstan Duckett, Jennita Reefhuis, Jamie Kim, Jennifer Isenburg, Katherine Zielke, Jing Shi, Kristen St John, Sook Ja Cho, Tyiesha D Short, Carolina Clark, My-Phuong Huynh, Tri Manh Tran, Nina E Forestieri, Leslie A. O'Leary, Deborah J. Fox, Mahsa M. Yazdy, Xiaoli Chen, Emily Ferrell, Jane Fornoff, Norm Nelson, Brennan Martin, Colin Benusa, Glenda M Ramirez, Michele K. Bohm, Mary K. Ethen
Rok vydání: 2019
Předmět:
Zdroj: Morbidity and Mortality Weekly Report
ISSN: 1545-861X
0149-2195
Popis: Prevalence of gastroschisis, a serious birth defect of the abdominal wall resulting in some of the abdominal contents extending outside the body at birth, has been increasing worldwide (1,2). Gastroschisis requires surgical repair after birth and is associated with digestive and feeding complications during infancy, which can affect development. Recent data from 14 U.S. states indicated an increasing prevalence of gastroschisis from 1995 to 2012 (1). Young maternal age has been strongly associated with gastroschisis, but research suggests that risk factors such as smoking, genitourinary infections, and prescription opioid use also might be associated (3-5). Data from 20 population-based state surveillance programs were pooled and analyzed to assess age-specific gastroschisis prevalence during two 5-year periods, 2006-2010 and 2011-2015, and an ecologic approach was used to compare annual gastroschisis prevalence by annual opioid prescription rate categories. Gastroschisis prevalence increased only slightly (10%) from 2006-2010 to 2011-2015 (prevalence ratio = 1.1, 95% confidence interval [CI] = 1.0-1.1), with the highest prevalence among mothers aged
Databáze: OpenAIRE