Clinical Features of Mycobacterium canettii Infection: A Retrospective Study of 20 Cases Among French Soldiers and Relatives
| Autor: | Michel Fabre, Frédéric Rivière, Charles Soler, Jean-Baptiste Roseau, Emilie Javelle, Marc Aletti, Fabrice Simon, Anaïs Briquet, Nicolas Cazes, Rithy Vong, S. Duron, Marie-Pierre Otto, Cécile Ficko, Christine Pourcel |
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| Přispěvatelé: | Département de Pneumologie, Centre Hospitalier Sainte Anne, Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Service de Santé des Armées, CHU CLAMART, Laboratoire de biologie médicale, Service de Santé des Armées-Hôpital d'instruction des Armées Percy, Hôpital d'Instruction des Armées Begin, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'épidémiologie et de santé publique des armées [Marseille] (CESPA), Centre de recherche en éducation de Nantes (CREN), Le Mans Université (UM)-Université de Nantes - UFR Lettres et Langages (UFRLL), Université de Nantes (UN)-Université de Nantes (UN), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Département Biologie des Génomes (DBG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Hôpital d'instruction des Armées Percy, Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA), Université de Nantes - UFR Lettres et Langages (UFRLL), Université de Nantes (UN)-Université de Nantes (UN)-Le Mans Université (UM), SERRE, Marie-Claude |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male 0301 basic medicine Microbiology (medical) medicine.medical_specialty Pediatrics Tuberculosis Adolescent [SDV]Life Sciences [q-bio] 030106 microbiology Mycobacterium Young Adult 03 medical and health sciences Epidemiology medicine Humans Child Immunodeficiency Retrospective Studies Mycobacterium Infections biology business.industry Public health Infant Retrospective cohort study Adenitis Middle Aged medicine.disease biology.organism_classification 3. Good health [SDV] Life Sciences [q-bio] Military personnel Military Personnel 030104 developmental biology Infectious Diseases Mycobacterium tuberculosis complex Child Preschool Female business |
| Zdroj: | Clinical Infectious Diseases Clinical Infectious Diseases, 2019, ⟨10.1093/cid/ciz107⟩ Clinical Infectious Diseases, Oxford University Press (OUP), 2019, ⟨10.1093/cid/ciz107⟩ |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1093/cid/ciz107 |
| Popis: | Background Mycobacterium canettii forms part of the Mycobacterium tuberculosis complex. Mycobacterium canettii infections are mainly described in the Horn of Africa. The permanent presence of French soldiers in Djibouti raises the question of the risk of being infected with M. canettii. Here, we describe M. canettii infections among French military and their families between 1998 and 2015. Methods This retrospective study relied on 3 sources of data: the reference center for mycobacteria in the Biology Department at Percy Military Hospital in Paris, the French Military Center for Epidemiology and Public Health, and the scientific literature. After an exhaustive census of the strains, we studied the epidemiological data on 20 cases among French soldiers and their families. Results Twenty cases of M. canettii infections are reported, including 5 unpublished cases. Adenitis predominates (n = 15), especially in the cervico facial area and among children; 1 case was observed 1 month after dental care in Djibouti. The pulmonary forms were less frequent (n = 6), and 3 atypical forms are described. All patients had stayed in Djibouti. Conclusions Cases of M. canettii infection among the French military consisted mainly of adenitis; disseminated forms were possible with immunodeficiency. Their evolution under specific treatments was comparable to that of tuberculosis. The presumed origin of the infection seemed to be environmental, possibly a water reservoir, and not due to human-to-human contagion. |
| Databáze: | OpenAIRE |
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