The potential relationship between QTc interval prolongation and ziprasidone treatment: three cases

Autor:	Saygın Eker, Selçuk Kirli, Aslı Sarandöl, Cengiz Akkaya, Enver Yusuf Sivrioglu
Přispěvatelé:	Uludağ Üniversitesi/Tıp Fakültesi/Psikiyatri Anabilim Dalı., Eker, Salih Saygın, Sarandol, Aslı, Akkaya, Cengiz, Sivrioğlu, Enver Yusuf, Kırlı, Selçuk, Q-9477-2019
Rok vydání:	2008
Předmět:	Male medicine.medical_treatment Torsade-de-pointes Piperazines Antipsychotic Drug blood level Electrocardiography Diabetes mellitus Valproic acid Pharmacology (medical) Priority journal Psychiatry Drug withdrawal medicine.diagnostic_test Glimepiride Prolongation Double-blind Venlafaxine Middle Aged Metformin Management Psychiatry and Mental health Acute exacerbation Schizophrenia Anesthesia Clinical neurology cardiovascular system Drug dose reduction 160 mg/day Female Safety Amisulpride Ziprasidone Drug dose increase medicine.drug circulatory and respiratory physiology Human Antipsychotic Agents Adult congenital hereditary and neonatal diseases and abnormalities Schizoaffective disorder Heart block medicine.drug_class Zuclopenthixol decanoate Drug response Atypical antipsychotic Diagnostic and statistical manual of mental disorders QT prolongation Lithium Neurosciences & neurology QT interval Article Biperiden Drug substitution Antipsychotic-drugs Case report medicine Humans cardiovascular diseases Disease exacerbation Pharmacology business.industry Pharmacology & pharmacy Quetiapine Neurosciences medicine.disease Psychosis Neuroleptic Agent Drug efficacy Thiazoles Haloperidol business QTc prolongation Bornaprine
Zdroj:	Journal of psychopharmacology (Oxford, England). 23(8)
ISSN:	1461-7285
Popis:	QTc interval prolongation may appear as a consequence of both typical and atypical antipsychotic treatments. Ziprasidone, which is effective in treating schizophrenia, is associated with QTc prolongation. Although the prolongation of QTc with ziprasidone treatment is often pronounced, there is a scarce number of cases reported about the relationship between ziprasidone and QTc prolongation. Of the three cases presented in this case series, two cases showed values exceeding 0.50 s with ziprasidone treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8daf9f621ffd9b0b0792eccedcd464e7 https://pubmed.ncbi.nlm.nih.gov/18635710 Zobrazit plný text záznamu