Zoster vaccine-associated primary varicella infection in an immunocompetent host
| Autor: | Marietta Vázquez, Kaoru Harada, Jason Chen, Jaimie P. Meyer, Henry Heaton |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
Vesicular rash Fever viruses Acyclovir Single-nucleotide polymorphism medicine.disease_cause Antiviral Agents Article Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Vaccine strain Herpes Zoster Vaccine Humans Medicine 030212 general & internal medicine Infusions Intravenous integumentary system business.industry Host (biology) Varicella zoster virus virus diseases General Medicine Middle Aged Virology Varicella Zoster Virus Infection Varicella infection Transaminitis Zoster vaccine business Immunocompetence 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | BMJ Case Reports. :bcr-2017 |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2017-221166 |
| Popis: | A 64-year-old immunocompetent man developed a widespread pruritic and vesicular rash 2 weeks after receiving the zoster vaccine (Zostavax). He had fever, bandaemia with normal total white blood cell count and mild transaminitis. PCR testing of serum and skin was positive for varicella zoster virus (VZV), while serum VZV IgG was negative. The analysis of single nucleotide polymorphism by PCR and sequencing from the skin swab was consistent with the vaccine strain. The patient received 1 week of intravenous acyclovir and was discharged after all lesions had crusted. He continues to do well on follow-up with no significant complications. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|