Treatment of active distal ulcerative colitis with immunoglobulin G enemas
| Autor: | B. Faber Vestergaard, R. Mølskov Bech, A. E. Jarløv, P. Nordblad Schmidt, Pia Munkholm, Ebbe Langholz |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Enema Gastroenterology Bedtime Immunoglobulin G Feces Administration Rectal Internal medicine medicine Humans Pharmacology (medical) Sigmoidoscopy Sigmoidoscopy with Biopsy Hepatology biology business.industry Rectum Acute-phase protein Proteins Immunotherapy Middle Aged medicine.disease Ulcerative colitis Rectal administration biology.protein Colitis Ulcerative Female business |
| Zdroj: | Alimentary Pharmacology & Therapeutics. 7:561-565 |
| ISSN: | 1365-2036 0269-2813 |
| DOI: | 10.1111/j.1365-2036.1993.tb00133.x |
| Popis: | SUMMARY Seven patients with active distal ulcerative colitis were treated with IgG enemas given as a daily bedtime retention enema for two weeks. Evaluation of effect was assessed by means of sigmoidoscopy with biopsy, measuring acute phase reactants in peripheral blood, and measuring the faecal protein loss. Clinical signs of active disease were registered by the patients on a diary chart. Five patients completed the treatment period, two patients were withdrawn after 7 and 10 days due to deterioration of disease. Four patients did not register any effect, whereas one patient improved clinically. In conclusion, rectally administered IgG did not exert any effect on rectal ulcerative colitis in our study. |
| Databáze: | OpenAIRE |
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