Genetic Characterization of Enterovirus A71 Circulating in Africa
| Autor: | Ousmane Kebe, Michael R. Wiley, Javier Martin, Maël Bessaud, Francis Delpeyroux, Maria Dolores Fernandez-Garcia, Serge Alain Sadeuh-Mba, Manasi Majumdar, Gustavo Palacios, Romain Volle, Ionela Gouandjika-Vasilache, Anavaj Sakuntabhai, Etienne Simon-Loriere, Marie-Line Joffret, Kader Ndiaye |
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| Přispěvatelé: | Institut Pasteur de Dakar, Réseau International des Instituts Pasteur (RIIP), Institut Pasteur [Paris], Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Pasteur du Cameroun, Institut Pasteur de Bangui, University of Nebraska Medical Center, University of Nebraska System, U.S. Army Medical Research Institute of Infectious Diseases, National Institute for Biological Standards and Control (NIBSC), Medicines and Healthcare Products Regulatory Agency (MHRA), The next-generation sequencing equipment at Institut Pasteur of Dakar was provided by the Defense Biological Product Assurance Office under the Targeted Acquisition of Reference Materials Augmenting Capabilities Initiative. This work was supported by the IPD, the Pasteur Institute’s Transverse Research Program PTR484, Actions Concertées Inter-Pasteuriennes A22-16, Fondation Total Grant S-CM15010-05B, Roux Howard Cantarini postdoctoral fellowship, and Grant Calmette and Yersin from the International Directorate of the Institut Pasteur., We thank Karla Prieto and Catherine Pratt, who assisted in obtaining nearly complete genomes of West Africa strains, and Joseph Chitty for analysis of the next-generation sequencing data., Institut Pasteur [Paris] (IP), U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Acute flaccid paralysis Genotype Epidemiology viruses lcsh:Medicine Genome Viral Biology medicine.disease_cause West africa lcsh:Infectious and parasitic diseases 03 medical and health sciences [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Genetic Characterization of Enterovirus A71 Circulating in Africa medicine Enterovirus Infections Humans lcsh:RC109-216 Phylogeny Recombination Genetic [SDV.GEN]Life Sciences [q-bio]/Genetics whole-genome analysis enterovirus phylogenetic analysis lcsh:R Dispatch Genetic Variation virus diseases Enterovirus a71 Virology recombination Enterovirus A Human 030104 developmental biology Infectious Diseases enterovirus A71 Africa Enterovirus [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie acute flaccid paralysis |
| Zdroj: | Emerging Infectious Diseases, Vol 24, Iss 4, Pp 754-757 (2018) Emerging Infectious Diseases Emerging Infectious Diseases, Centers for Disease Control and Prevention, 2018, 24 (4), pp.754-757. ⟨10.3201/eid2404.171783⟩ Emerging Infectious Diseases, 2018, 24 (4), pp.754-757. ⟨10.3201/eid2404.171783⟩ |
| ISSN: | 1080-6059 1080-6040 |
| DOI: | 10.3201/eid2404.171783⟩ |
| Popis: | International audience; We analyzed whole-genome sequences of 8 enterovirus A71 isolates (EV-A71). We confirm the circulation of geno-group C and the new genogroup E in West Africa. Our analysis demonstrates wide geographic circulation and describes genetic exchanges between EV-A71 and autochtho-nous EV-A that might contribute to the emergence of patho-genic lineages. |
| Databáze: | OpenAIRE |
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