Clinical, Occupational and Allergological Profile of 455 Patients with Occupational Contact Dermatitis: A 5-Year Study from a Tertiary Care Center of North India

Autor:	Pushpinder S Chauhan, Jyotshna Sharma, Karaninder S Mehta, Hitender Sharma, Vijay Karan Singh, Sheenam Hooda, Yog Raj Verma, Monika Chandel, Vikram K Mahajan, Anuj Sharma, Reena Sharma
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	medicine.medical_specialty Airborne contact dermatitis chemistry.chemical_compound parthenium facial dermatitis medicine hand dermatitis Occupational contact dermatitis Allergic contact dermatitis Potassium dichromate patch testing biology business.industry Patch test medicine.disease biology.organism_classification Dermatology Indian standard series Parthenium chemistry occupational contact dermatitis Hand dermatitis Mercaptobenzothiazole Original Article business allergic contact dermatitis Contact dermatitis
Zdroj:	Indian Dermatology Online Journal
ISSN:	2249-5673 2229-5178
Popis:	Objectives: To evaluate clinical and occupational profile and common allergens in patients with occupational contact dermatitis (OCD). Materials and Methods: The records of 455 (M:F 2:1) patients aged 18-85 years with allergic contact dermatitis were analyzed retrospectively. The diagnosis of OCD and patterns of dermatitis were defined by standard criteria. Indian standard series comprising 20 allergens and when suspected patient's own products were patch tested by Finn chamber method as per European Society of Contact Dermatitis guidelines and relevance of positive results was defined clinically. Results: Airborne contact dermatitis (27.7%), acral dermatitis (14.1%), hand dermatitis (12.9%), acrofacial dermatitis (12.7%), and facial dermatitis (10.5%) were the common patterns. Agriculturists (51.2%), homemakers (27.9%), office workers (24.6%), and construction workers (4.6%) comprised the majority. Positive patch test results in 58% cases were from parthenium (31.7%), p-paraphenylenediamine (PPD) (22.9%), nickel (16%), fragrance mix (11%), potassium dichromate (10.7%), cobalt (7.6%), and mercaptobenzothiazole (4.9%). Hair colorants, shoe chips, and shaving cream also produced relevant positive reactions. Parthenium, PPD, fragrance mix, and potassium dichromate in agriculturists; nickel, parthenium, PPD, fragrance mix, and potassium dichromate in women, and potassium dichromate and parthenium in construction workers elicited the most positive reactions. PPD and hair colorants elicited positive reaction mainly in office workers. Conclusions: The agriculturists, homemakers, and construction workers have OCD most frequently. Parthenium in farmers, potassium dichromate in construction workers, nickel in women, and PPD in office workers were the major contact allergens. The study is limited by its retrospective design, small number of patients, and limited number of patch test allergens.
Databáze:	OpenAIRE
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