Autor: |
Tatsuya Tai, Kazunori Yamaguchi, Naohiro Kurokawa, Wataru Shinmura, Aki Matsubara, Masahiro Watanabe, Takahiro Motoki, Hiroaki Tanaka, Hitoshi Houchi, Shinji Kosaka |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 142(7) |
ISSN: |
1347-5231 |
Popis: |
We report a haemodialysis patient with end-stage renal failure whom a pharmacist aided in the management of acyclovir (ACV) encephalopathy, which may have been related to valacyclovir hydrochloride (VACV) administered without sufficient dose reduction. The patient 78 years was admitted with a tentative diagnosis of varicella zoster viral meningitis. A pharmacist suspected ACV encephalopathy related to excessive VACV administration and raised a query with the attending physician. According to the pharmacist's proposal, ACV administration was discontinued and continuous hemodiafiltration (CHDF) was performed. On day 5 of hospitalisation, the consciousness disorder was improved. In this report, we showed the detailed CHDF conditions of the present case, and the contribution of a pharmacist to treating and avoiding ACV encephalopathy was discussed. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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