Distance between the center of the FAZ measured automatically and the highest foveal bulge using OCT-angiography in elderly healthy eyes
| Autor: | Hisashi Ibuki, Kei Shinoda, Takuhei Shoji, Hirokazu Ishii, Junji Kanno, Yuji Yoshikawa, Takanori Sasaki |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Fovea Centralis medicine.medical_specialty Visual acuity Capillary plexus genetic structures Fundus Oculi Science Visual Acuity Article Foveola Oct angiography Foveal Ophthalmology medicine Humans Center (algebra and category theory) Fluorescein Angiography Aged Multidisciplinary business.industry Retinal Vessels Optical coherence tomography angiography Foveal avascular zone Healthy Volunteers eye diseases Cross-Sectional Studies Medicine Female Medical imaging sense organs Anatomy medicine.symptom business Tomography Optical Coherence |
| Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021) Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | The center of the fovea, termed the foveola, is the area of highest visual acuity, has the highest density of cone photoreceptors. We investigated the distance between the automatically-determined center of the foveal avascular zone (FAZ) and the manually-determined highest foveal bulge (FB) point using single swept-source optical coherence tomography angiography (OCTA) instrument. This cross-sectional study included 49 eyes of 49 individuals (34 women and 15 men; median age: 68 years) with no history of ocular disorders. The FAZ in the superficial capillary plexus was automatically determined using the Kanno–Saitama macro method, and the center of the FAZ was automatically determined using ellipse approximation. Another candidate foveal center, the highest FB point, was determined manually on the serial cross-sectional B-scan images. As a result, the foveal center was manually identified as the highest FB point on B-scan OCTA images. The center of the FAZ was more likely to be located inferior to the highest FB point (p = 0.031). In participants with a total (linear) distance of more than 50 μm between the center of the FAZ and the highest FB point, the displacement was significantly more in the horizontal direction than in the vertical direction (p = 0.017). These results can be applicable to further studies regarding the spatial relationships between the center of the FAZ and the highest FB point in various macular diseases or previously-treated eyes. |
| Databáze: | OpenAIRE |
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