Nasogastric tube feeding in children with cancer: the effect of two different formulas on weight, body composition, and serum protein concentrations

Autor: E. den Broeder, Jules J. M. Tolboom, Z. Hofman, A. M. J. van den Berg, R.J.J. Lippens, N. B. M. van Houdt, W.A. van Staveren, M.A. van 't Hof, Rob C.A. Sengers
Rok vydání: 2000
Předmět:
Cachexia
Time Factors
030309 nutrition & dietetics
medicine.medical_treatment
Medicine (miscellaneous)
Gastroenterology
law.invention
Treatment of children with solid tumors
0302 clinical medicine
Randomized controlled trial
law
Neoplasms
Intubation
Prospective Studies
Prospective cohort study
Child
Intubation
Gastrointestinal
Human Nutrition & Health
0303 health sciences
Nutrition and Dietetics
Anthropometry
Humane Voeding & Gezondheid
Blood Proteins
Blood proteins
Treatment Outcome
Child
Preschool
Vomiting
Body Composition
030211 gastroenterology & hepatology
medicine.symptom
medicine.medical_specialty
Adolescent
Behandelingsresultaten bij kinderen met solide tumoren
Nutritional Status
03 medical and health sciences
Enteral Nutrition
Double-Blind Method
Internal medicine
medicine
Humans
Life Science
VLAG
Food
Formulated
business.industry
Body Weight
Infant
medicine.disease
Endocrinology
Parenteral nutrition
business
Energy Intake
Zdroj: Journal of Parenteral and Enteral Nutrition, 24(6), 351-360
Journal of Parenteral and Enteral Nutrition 24 (2000) 6
Jpen, Journal of Parenteral and Enteral Nutrition, 24, 351-360
Jpen, Journal of Parenteral and Enteral Nutrition, 24, 6, pp. 351-360
ISSN: 0148-6071
DOI: 10.1177/0148607100024006351
Popis: Background: Treatment of cancer cachexia partly involves the administration of adequate amounts of energy. The aim of this study was to assess the tolerance and efficacy of two equal volumes of tube feeding, one with a standard (1 kcal/mL) and one with a high energy density (1.5 kcal/mL), during the intensive phase of treatment. Methods: Nutritional status was assessed weekly, in 27 children with a solid tumor, by measuring weight, height, midupper arm circumference, biceps and triceps skinfold, and serum proteins. Tolerance was assessed by recording the occurrence of vomiting and by expressing the administered volume as a percentage of the required volume. Results: Both formulas were equally well tolerated, leading to a significantly higher energy intake in the energy-enriched formula group. In both formula groups, all anthropometric variables increased significantly (range of mean increase, 5.2% to 25.5%; p < .05) during the first 4 weeks of intervention. Between 4 and 10 weeks, variables continued to increase significantly in the energy-enriched group, resulting in adequate repletion, in contrast to the standard formula group. The concentration of serum proteins, low at initiation of tube feeding, returned to the normal range within 2 to 4 weeks with no significant differences between the two groups. Conclusions: The energy-enriched formula was more effective in improving the nutritional status of children with cancer during the intensive phase of treatment than the standard formula. Intensive, protocolized administration of an energy-enriched formula should therefore be initiated as soon as one of the criteria for initiation of tube feeding is met.
Databáze: OpenAIRE
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