Influence of False Lumen Status on the Prognosis of Acute Type A Aortic Dissection without Urgent Surgical Treatment
Autor: | Akihiko Usui, Tomoyuki Ota, Hideki Oshima, Hideki Ishii, Akihito Tanaka, Toyoaki Murohara, Kimihiro Komori, Susumu Suzuki |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Partial thrombosis
Male medicine.medical_specialty False lumen status False lumen 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal Medicine medicine Humans 030212 general & internal medicine Surgical treatment Aorta Aged Aortic dissection business.industry Mortality rate Biochemistry (medical) Significant difference Endovascular Procedures Thrombosis medicine.disease Type A aortic dissection Prognosis Surgery Aortic Aneurysm Aortic Dissection Acute type Acute Disease Original Article Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
Zdroj: | Journal of Atherosclerosis and Thrombosis |
ISSN: | 1880-3873 1340-3478 |
Popis: | Aim: Recently, much attention has been focused on partial thrombosis of the false lumen in patients with acute aortic dissection. However, its effect on clinical outcomes in these patients, especially in case of acute type A aortic dissection, has not been clearly elucidated. This study evaluated the influence of the false lumen status, including partial thrombosis, on short-term clinical outcomes in acute type A aortic dissection patients without urgent surgical treatment. Methods: Sixty-two patients (29 males, mean age 73 ± 13 years) with acute type A aortic dissection who did not receive urgent surgical treatment at four hospitals were enrolled. Patients were divided into three groups based on the false lumen status on enhanced computed tomography image (complete thrombosis, n = 28; partial thrombosis, n = 27; patent, n = 7). Patients with partial thrombosis were further divided into two groups (thrombus-dominant, n = 15; flow-dominant, n = 12). Results: The short-term mortality rate (in-hospital and 30-day) was significantly higher in patients with a patent false lumen, while no significant difference was seen between the other two groups. Patients with flow-dominant partial thrombosis had significantly higher short-term mortality rate than those with thrombus-dominant partial thrombosis (in-hospital, p = 0.001 and 30-day, p < 0.001). Conclusions: The short-term mortality rate in acute type A aortic dissection patients without urgent surgical treatment was lower in patients with partial thrombosis of the false lumen than in those with a patent false lumen. Furthermore, patients with flow-dominant partial thrombosis had higher mortality rate than those with thrombus-dominant partial thrombosis. |
Databáze: | OpenAIRE |
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