Integrated personalized diabetes management improves glycemic control in patients with insulin-treated type 2 diabetes: Results of the PDM-ProValue study program
| Autor: | Wendelin Schramm, Christopher G. Parkin, Diethelm Messinger, Iris Vesper, Bernhard Kulzer, Joerg Weissmann, Ingrid Daenschel, Lutz Heinemann, Wilfried Daenschel |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism Hypoglycemic episodes Type 2 diabetes 03 medical and health sciences 0302 clinical medicine Endocrinology Diabetes management Diabetes mellitus Internal Medicine Humans Hypoglycemic Agents Insulin Medicine In patient Prospective Studies 030212 general & internal medicine Aged Glycemic Glycated Hemoglobin business.industry Blood Glucose Self-Monitoring General Medicine Middle Aged Prognosis medicine.disease Diabetes Mellitus Type 2 Glycemic Index Research Design Usual care Emergency medicine Female business |
| Zdroj: | Diabetes Research and Clinical Practice. 144:200-212 |
| ISSN: | 0168-8227 |
| Popis: | Globally, many patients with insulin-treated type-2 diabetes are suboptimally controlled. The PDM-ProValue study program evaluated whether integrated personalized diabetes management (iPDM) has the potential to improve clinical outcomes.101 practices with 907 patients participated in the 12-month, prospective, controlled, cluster-randomized study program. HbA1c levels, therapy changes, frequency of hypoglycemic episodes, patient reported outcomes, and physician satisfaction were assessed.iPDM led to a greater reduction in HbA1c after 12 months vs. usual care (-0.5%, p 0.0001 vs. -0.3%, p 0.0001), (Diff. 0.2%, p = 0.0324). Most of the HbA1c reduction occurred after 3 months and remained stable thereafter. The percentage of patients with therapy adjustments was higher in the iPDM group at all visits (p 0.01 at week 3, month 3, month 6). Patient adherence at month 12 was higher in the iPDM group compared to baseline (Odds ratio = 2.39; p = 0.0003); also, patient treatment satisfaction (DTSQc: 12.2 vs. 10.4, δ = 1.78, p = 0.004; DTSQs: 31.0 vs. 30.0, δ = 0.924, p = 0.02), and physician satisfaction was higher in the intervention group.iPDM improved the use of diagnostic data leading to better glycemic control, more timely treatment adjustments (indicating reduced clinical inertia), and increased patient adherence and treatment satisfaction among patients and physicians. |
| Databáze: | OpenAIRE |
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