Differences in response of the proximal esophagus to wet swallows in patients of Chagas' disease and idiopathic achalasia
| Autor: | L. M. M. Varrica, Roberto Oliveira Dantas, R. I. Ramos |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Chagas disease
Adult Male medicine.medical_specialty Time Factors Manometry Contrast Media Gastroenterology Esophagus Swallowing Internal medicine otorhinolaryngologic diseases medicine Humans Chagas Disease Aged Retrospective Studies Aged 80 and over Esophageal disease business.industry Area under the curve Megaesophagus General Medicine Middle Aged medicine.disease Deglutition Esophageal Achalasia Radiography medicine.anatomical_structure Concomitant Case-Control Studies Esophageal dilatation Pharyngeal Muscles Female Barium Sulfate business Muscle Contraction |
| Zdroj: | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 19(5) |
| ISSN: | 1120-8694 |
| Popis: | SUMMARY. Chagas’ disease and idiopathic achalasia have similar esophageal manifestations such as absent or incomplete lower esophageal sphincter relaxation and aperistalsis in the esophageal body (alterations seen mainly in the distal esophageal body). Our aim in this paper was to study the response of the proximal esophageal body to wet swallows in patients with Chagas’ disease and patients with idiopathic achalasia. We retrospectively analyzed the time interval between the onset of the pharyngeal contractions 1 cm proximal to the upper esophageal sphincter, as well as 5 cm distal to the pharyngeal measurement. Amplitude, duration and area under the curve of contractions in the proximal esophagus were also determined in 42 patients with Chagas’ disease (15 with associated esophageal dilatation), 21 patients with idiopathic achalasia (14 with concomitant esophageal dilatation) and 31 control subjects. The time between the onset of pharyngeal and proximal esophageal contractions was longer in patients with Chagas’ disease and in those with esophageal dilatation (1.39 ± 0.16 s) than in control subjects (0.86 ± 0.04 s, P |
| Databáze: | OpenAIRE |
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