Method for detection of picornavirus capsid binders with soluble intercellular adhesion molecule 1
Autor: | Deborah D. Jeanfavre, K Pal, Eugene J. McNally, C Cahill-Feehan, Vincent J. Merluzzi, Steven D. Marlin, Kathleen Last-Barney |
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Rok vydání: | 1993 |
Předmět: |
Picornavirus
Rhinovirus viruses Intercellular Adhesion Molecule-1 Biotin Enzyme-Linked Immunosorbent Assay Picornaviridae medicine.disease_cause chemistry.chemical_compound Capsid medicine Humans Pharmacology (medical) Pharmacology biology Cell adhesion molecule Adhesion biochemical phenomena metabolism and nutrition biology.organism_classification Thiazoles Infectious Diseases Biochemistry chemistry Solubility Biotinylation Cell Adhesion Molecules HeLa Cells Research Article |
Zdroj: | Antimicrobial agents and chemotherapy. 37(8) |
ISSN: | 0066-4804 |
Popis: | A method utilizing immobilized major group rhinoviruses and biotinylated soluble intercellular adhesion molecule 1 has been developed for the detection of capsid binders. Binding measurements indicate a loss in relative affinity of biotinylated soluble intercellular adhesion molecule 1 for rhinoviruses by capsid binders. This method and a new class of capsid binders are discussed. |
Databáze: | OpenAIRE |
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