Preparation and Antibacterial Activity of Copper and Cobalt Complexes of 4-Chloro-3-nitrobenzoate with a Nitrogen Donor Ligand
| Autor: | Amer M. Ghannoum, Ahmad T. Kabbani, Hassan H. Hammud |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Nitrogen
Inorganic chemistry Molecular Conformation chemistry.chemical_element Microbial Sensitivity Tests Ligands Enterococcus faecalis Drug Discovery Fourier transform infrared spectroscopy Thermal analysis Bacteria biology Ligand Cobalt General Chemistry General Medicine biology.organism_classification Copper Anti-Bacterial Agents Chlorobenzoates chemistry Antibacterial activity Nuclear chemistry |
| Zdroj: | Chemical and Pharmaceutical Bulletin. 55:446-450 |
| ISSN: | 1347-5223 0009-2363 |
| Popis: | Copper and cobalt complexes with 4-chloro-3-nitrobenzoate (ClNBz) and the nitrogen ligands 1,3-diaminopropane (1,3-DAP) or o-phenylenediamine (o-PDA), were prepared and characterized. The complexes [Cu(ClNBz)2(1,3-DAP)] (1), [Cu(ClNBz)(o-PDA)]Cl (2), [Co(ClNBz)2(1,3-DAP)] (3) and [Co(ClNBz)2(o-PDA)2] (4) were characterized by FTIR, UV-Visible absorption, elemental analysis and thermal analysis. Complex [Cu(ClNBz)(o-PDA)]Cl (2) shows high antibacterial activity as indicated by its ability to inhibit the growth of Staphylococcus aureus, Enterococcus faecalis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|