Diffuse amyloid deposition in thyroid gland: a cause for concern in familial Mediterranean fever
| Autor: | Metin Arslan, Nesibe Cesur, Ozlem Turhan Iyidir, Ayhan Karakoç, Mustafa Altay, İpek Işık Gönül, Turgay Arinsoy, Ceyla Konca Degertekin, Kürşad Öneç, Göksun Ayvaz, Alev Eroglu Altinova |
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| Rok vydání: | 2012 |
| Předmět: |
endocrine system
Pathology medicine.medical_specialty Goiter endocrine system diseases Amyloid Thyroid Gland Familial Mediterranean fever Plaque Amyloid Fatal Outcome Parenchyma Biopsy Internal Medicine Medicine Humans medicine.diagnostic_test business.industry Amyloidosis Thyroid Middle Aged medicine.disease Familial Mediterranean Fever Fine-needle aspiration medicine.anatomical_structure Female business |
| Zdroj: | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 19(3) |
| ISSN: | 1744-2818 |
| Popis: | Thyroid gland is among the many organs that could be infiltrated in systemic amyloidosis. However, diffuse infiltration of the thyroid gland secondary to systemic amyloidosis associated with Familial Mediterranean fever (FMF) is rare. Here, we present a 49-year-old woman diagnosed with FMF and systemic amyloidosis, who had a large goiter and multiple nodules that developed slowly through the years and was complicated by tracheal compression symptoms and a mild thyroid dysfunction. Multiple fine needle aspiration biopsies of the nodules and the thyroid parenchyma revealed amyloid deposits. We would like to point out that amyloidosis may have a significant impact on the thyroid gland and fine needle aspiration biopsy is a valuable tool for diagnosis. |
| Databáze: | OpenAIRE |
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