Restless legs syndrome
| Autor: | Heinz Reichmann, Kalyan Bhattacharya, Lisa Klingelhoefer |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Dopamine agent business.industry Dopamine Agents Dopaminergic CME SECTION: CME Movement disorders General Medicine Disease medicine.disease 3. Good health 03 medical and health sciences 0302 clinical medicine Pharmacological interventions Physical medicine and rehabilitation Restless Legs Syndrome mental disorders medicine Humans Treatment strategy Willis-Ekbom disease 030212 general & internal medicine Restless legs syndrome Complication business 030217 neurology & neurosurgery |
| Zdroj: | Clinical Medicine. 16:379-382 |
| ISSN: | 1473-4893 1470-2118 |
| DOI: | 10.7861/clinmedicine.16-4-379 |
| Popis: | Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is a common movement disorder characterised by an uncontrollable urge to move because of uncomfortable, sometimes painful sensations in the legs with a diurnal variation and a release with movement. The pathophysiology is only partially known and a genetic component together with dopaminergic and brain iron dysregulation plays an important role. Secondary causes for RLS need to be excluded. Treatment depends on the severity and frequency of RLS symptoms, comprises non-pharmacological (eg lifestyle changes) and pharmacological interventions (eg dopaminergic medication, alpha-2-delta calcium channel ligands, opioids) and relieves symptoms only. Augmentation is the main complication of long-term dopaminergic treatment of RLS. This article will provide a clinically useful overview of RLS with provision of diagnostic criteria, differential diagnoses, possible investigations and different treatment strategies with their associated complications. |
| Databáze: | OpenAIRE |
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