Parathyroid cancer - difficult diagnosis - a case report
| Autor: | Katarzyna Strawa-Zakościelna, Beata Matyjaszek-Matuszek, Beata Chrapko, Dawid Pyzik, Agnieszka Zwolak, Aleksandra Pyzik |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Parathyroid hormone 030209 endocrinology & metabolism Scintigraphy Sensitivity and Specificity Diagnosis Differential 03 medical and health sciences 0302 clinical medicine medicine Humans Radiology Nuclear Medicine and imaging Radionuclide Imaging Hyperparathyroidism medicine.diagnostic_test business.industry Mediastinum Cancer Magnetic resonance imaging General Medicine Middle Aged medicine.disease Radiography medicine.anatomical_structure Parathyroid Neoplasms 030220 oncology & carcinogenesis Radiology Differential diagnosis business hormones hormone substitutes and hormone antagonists Primary hyperparathyroidism |
| Zdroj: | Nuclear medicine review. CentralEastern Europe. 19(1) |
| ISSN: | 1644-4345 |
| Popis: | Parathyroid cancer is a rare disorder of unclear etiology that is difficult to diagnose and treat. It is most often diagnosed incidentally based on multi-organ non-specific symptoms of hypercalcemia as a consequence of parathyroid hormone oversecretion. We present a case of a male with primary hyperparathyroidism who was diagnosed with parathyroid cancer ectopically located in the mediastinum only after the third surgery. However, due to chronic hypercalcemia, problems with localization and a bad clinical condition, the patient was not able to undergo a radical resection and one year after the first pathological fracture died. Taking into consideration the whole clinical picture we want to emphasize the need to apply comprehensive differential diagnosis of hypercalcemia and localization diagnosis of parathyroid tissue with a use of MIBI scintigraphy accompanied by the computed tomography and magnetic resonance imaging, as the most specific diagnostic tools employed in this pathology. |
| Databáze: | OpenAIRE |
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