Hospital and 1-Year Outcomes of Septic Syndromes in Older People: A Cohort Study
| Autor: | Carlos Javier Regazzoni, Enrique A. Petrucci, Carlos M. Luna, Ariel K. Saad, Ana A Pisarevsky, Juan José Poderoso, Daniela De Mollein, Rafael J Zamora |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Aging medicine.medical_specialty Physical disability Argentina Sepsis syndrome Cohort Studies Sepsis Internal medicine Outcome Assessment Health Care medicine Humans Hospital Mortality Aged Proportional Hazards Models Aged 80 and over Proportional hazards model business.industry University hospital medicine.disease Systemic Inflammatory Response Syndrome Surgery Female Functional status Geriatrics and Gerontology Older people business Cohort study |
| Zdroj: | The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 63:210-212 |
| ISSN: | 1758-535X 1079-5006 |
| DOI: | 10.1093/gerona/63.2.210 |
| Popis: | Purpose. Our objective was to describe the relationship between sepsis syndrome mortality and cognitive and physical disability in elderly persons. Methods. A 1-year consecutive cohort study in clinical beds of a university hospital was performed. Variables were severity of sepsis syndrome, organ failure, functional status, age, sex, and positive cultures. Outcomes were in-hospital and 1-year mortalities. Results. The study included 137 patients (.70 years), both sexes. Data from 116 (84.5%) patients were obtainable at 1-year follow-up. Forty-eight (35%) patients presented with sepsis (11/137, 8%) or severe sepsis (37/137, 27%). Inhospital mortality was 15.3% (0% for sepsis and 21.8% if severe) and increased with organ failure ( p , .0001). One-year mortality was 54.78% (63/116), mostly related to severe sepsis; predictors were severe organ failure ( p , .0001), prior functional status ( p ¼ .0005), and Mini-Mental State Examination ( p ¼ .03). Prior functional status and organ failure were independent predictors. Conclusions. In-hospital and 1-year mortality increased with septic syndrome severity, prior functional status, and organ failure. |
| Databáze: | OpenAIRE |
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