Trends and Patterns of Breast Conservation Treatment in Hong Kong: 1994–2007
| Autor: | Mei-Wan Yeung, Inda S. Soong, T. K. Yau, Anne W.M. Lee, Henry Sze, Wai Tong Ng, Cheuk Wai Choi |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty Multivariate analysis medicine.medical_treatment Breast Neoplasms Mastectomy Segmental Breast Conservation Treatment Young Adult Breast cancer medicine Humans Radiology Nuclear Medicine and imaging Breast Young adult Aged Neoplasm Staging Retrospective Studies Aged 80 and over Gynecology Chi-Square Distribution Radiation Obstetrics business.industry Retrospective cohort study Organ Size Middle Aged medicine.disease Oncology Cohort Hong Kong Female business Chi-squared distribution Mastectomy Mammography |
| Zdroj: | International Journal of Radiation Oncology*Biology*Physics. 74:98-103 |
| ISSN: | 0360-3016 |
| DOI: | 10.1016/j.ijrobp.2008.07.066 |
| Popis: | Breast conservation treatment (BCT) was quite unpopular in Hong Kong until the early 1990s, but the trends and patterns of BCT use in the past 14 years have not been studied since. The purpose of this study was to identify the latest trends and patterns.All consecutive cases of female breast cancer referred to a community oncology center in Hong Kong between 1994 and 2007 were retrospectively reviewed. Of the 2,375 women with T1-2 invasive breast cancer who underwent surgery, 1,137 (48%) had T1 (/=2 cm) disease and 1,238 (52%) had T2 (2 cm-/=5 cm) disease. Median patient age was 51 years (range, 24-95 years); 65% patients had their surgery in public hospitals.Of the total patient cohort, 2,153 (91%) patients presented with palpable breast masses and only 104 (4%) with mammographically detected cancers. Overall, 721 (30%) and 1,654 (70%) patients underwent BCT and mastectomy, respectively. There was no significant increase in the BCT rates (31%, SD 5%; p = 0.804) or mammographic detection rates (5%, SD 1%; p = 0.125) in Hong Kong between 1994 and 2007. In multivariate analyses, age/=50 years (OR 2.479; p0.001), mammographically detected tumors (OR 1.868; p = 0.007), T1 tumors (OR 3.159; p0.001), surgeries in private hospitals (OR 1.288; p = 0.018), and negative nodal status (OR 1.886; p0.001) were independent factors predictive of a higher likelihood of a woman having BCT.Our results indicate a satisfactory acceptance of BCT by patients who are young and have small tumors, node-negative disease, or surgery in private hospitals. However, the continuing unpopularity of breast screening is likely a major factor limiting the broad use of BCT. |
| Databáze: | OpenAIRE |
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