MDR tuberculosis and HIV infection in the North-Western Federal District
| Autor: | Petr Yablonskiy, Y. Zhao, E. G. Sokolovich, Z. M. Zagdyn |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Tuberculosis prevalence Human immunodeficiency virus (HIV) medicine.disease_cause MDR Tuberculosis 03 medical and health sciences Diseases of the respiratory system 0302 clinical medicine Internal medicine Epidemiology medicine 030212 general & internal medicine hiv infection RC705-779 business.industry Incidence (epidemiology) 030206 dentistry General Medicine medicine.disease Multiple drug resistance tuberculosis treatment effectiveness Cohort Hiv patients incidence business multiple drug resistance |
| Zdroj: | Tuberkulez i Bolezni Lëgkih, Vol 99, Iss 1, Pp 27-32 (2021) |
| ISSN: | 2542-1506 2075-1230 |
| Popis: | The objective of the study : to study changes in MDR tuberculosis incidence and prevalence among patients with HIV infection in the North-Western Federal District and its regions in 2007-2018. Subjects and methods . The data from FSN Form No. 61 on Information on HIV Infected Patients Contingents for 2007-2018, materials of Federal Research Institute for Health Organization and Informatics by the Russian Ministry of Health, information from tables additionally developed by the authors were used. Epidemiological and statistical methods were applied; the differences between the variables were established by the Fisher coefficient based on the Statistica software. Results . The increase in the incidence of TB/HIV co-infection is the highest in regions with the low cumulation of HIV infection: Arkhangelsk, Pskov Regions and the Komi Republic. In 2018, MDR TB among HIV patients with HIV was the most prevalent in Leningrad Region (37.7%), the Komi Republic (32.2%) and Novgorod Region (29.3%), while in the Republic of Karelia, there was not a single case of MDR TB detected among HIV patients, in Pskov Region - 2.4% of cases. The efficacy of tuberculosis chemotherapy by regimens IV-V among the MDR TB/HIV cohort was statistically significantly lower than that of the entire MDR TB cohort: 41.4% versus 61.5% (p < 0.04). |
| Databáze: | OpenAIRE |
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